Baricitinib for the Treatment of Moderate-To-Severe Alopecia Areata

    January 2025 in “ Balkan Medical Journal ”
    Güllü Gencebay, Anıl Gülsel Bahalı, Didem Dizman, Melisa Özay, Özlem Su
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    TLDR Baricitinib helps regrow hair in severe alopecia areata and is safe, but more research is needed.
    This study assessed the effectiveness of baricitinib, a JAK inhibitor, in treating 14 patients with severe alopecia areata. Over 3 to 12 months, 57% of patients experienced at least a 50% improvement in hair regrowth, with 21% achieving complete regrowth. Adverse events were mild. The study concludes that baricitinib is effective and well-tolerated for treating refractory alopecia areata, but larger trials are necessary to confirm these results.
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