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The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Air pollution worsens skin diseases and aging by causing inflammation and oxidative stress.

The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Sebocytes play a key role in controlling androgen levels in human skin.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Chemotherapy can cause skin problems like hair loss, mouth sores, and skin darkening, and recognizing these can affect treatment decisions.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

Current treatments for alopecia show no significant long-term benefits.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

Liposomes improve drug delivery and reduce skin irritation in dermatology.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

The document recommends using both clinical evaluation and various measurement methods to assess skin greasiness, considering factors like temperature and hormones.

Different types of stem cells and their environments are key to skin repair and maintenance.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Stress can stop hair growth in mice, and treatments can reverse this effect.

No single treatment is consistently effective for alopecia areata, and more research is needed.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

Scientists turned rat thymus cells into stem cells that can help repair skin and hair.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.

Liposomes could improve how skin care products work but are costly and not very stable.

Skin surface lipids are important for skin health and altering them could help prevent aging and treat skin conditions.

Smoking may contribute to hair loss in men.