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research Stimulation by exosomes from hypoxia-preconditioned hair follicle mesenchymal stem cells facilitates mitophagy by inhibiting the PI3K/AKT/mTOR signaling pathway to alleviate ulcerative colitis
This study found that hypoxia-preconditioned HF-MSC-derived exosomes improved therapeutic outcomes in models of ulcerative colitis, potentially through miR-214-3p-mediated pathways affecting mitochondrial function and inflammatory responses.
research Pair Annotation: Adaption of Pair Programming to Corpus Annotation
This study found that greater root surface area due to root hairs contributed to better growth and zinc uptake of wild-type barley compared to its root-hairless mutant in zinc-deficient soil.
research Follicular Unit Excision Punches and Devices
This review discusses the various designs of follicular unit excision punches used in hair transplantation without reporting new clinical results; it emphasizes the importance of understanding each punch's benefits and limitations.
research An mTurq2-Col4a1 mouse model allows for live visualization of mammalian basement membrane development
This study developed the mTurquoise2-Col4a1 mouse model and used fluorescent tagging of collagen IV to offer new insights into basement membrane dynamics during hair follicle budding, revealing that basement membranes are flexible and stable structures in developing skin tissue.
research Virilizing Ovarian Tumor in a Postmenopausal Women
research 1458 EMT-inhibiting transcription factor Ovol2 regulates directional cell migration and proliferation in adult skin epithelia
This study found that the loss of transcription factor Ovol2 in epidermal and hair follicle stem cells leads to migration defects, which are partially improved by deleting the EMT-inducing Zeb1.
research Low level laser therapy in hair loss
Low level laser therapy may help with hair loss.
research 1406 DETECTION OF MEMBRANE ANDROGEN-BINDING SITE IN LIVING RAT PROSTATE AND EVALUATION OF ITS ROLE IN PROSTATE BLOOD FLOW REGULATION
This study found that ureteroileal anastomosis with direct intraluminal visualization had a 4.2% stricture rate, which compares favorably to other techniques with rates between 3.5% and 11.1%.
research SUPEROXIDE DISMUTASE LOADED NIOSOMES DELIVERY TO HAIR FOLLICLES: PERMEATION THROUGH SYNTHETIC MEMBRANE AND GUINEA PIG SKIN
This study explored the use of SOD-loaded niosomes as carriers to enhance the delivery of superoxide dismutase into hair follicles on guinea pig skin, finding that niosomes improved SOD penetration and preservation compared to free SOD, suggesting their potential as effective delivery vehicles.
research Follicular Unit Extraction
This article discusses the benefits, techniques, and unique considerations of follicular unit extraction for hair grafting, but reports no new clinical results.
research ALOPECIA TEMPORÁRIA APÓS TRATAMENTO ENDOVASCULAR RELACIONADA A UMA MALFORMAÇÃO ARTERIOVENOSA EM FACE: RELATO DE CASO
In this case report, a 34-year-old man experienced temporary hair loss after undergoing an endovascular procedure with fluoroscopy for facial arteriovenous malformation, which resolved within two months following treatment with topical Minoxidil and oral Cilostazol.
research The use of 5 alpha-reductase in the era of minimally invasive surgical therapies (MISTs): Is it still valuable?
research UTX (KDM6A) promotes differentiation noncatalytically in somatic self-renewing epithelia
In this study, researchers found that the histone demethylase UTX is crucial for regulating skin differentiation through retinoic acid signaling, mainly impacting females, as males compensate with a Y-linked paralog.
research Insights learned from L457(3.43)R, an activating mutant of the human lutropin receptor
This study found that the L457(3.43)R mutation in the human luteinizing hormone receptor increases phosphodiesterase activity, reducing hormonal response despite elevated basal cAMP levels.
research 5alpha-reductase inhibitors dampen L-DOPA-induced dyskinesia via normalization of dopamine D1-receptor signaling pathway and D1-D3 receptor interaction
This study found that both finasteride and dutasteride significantly reduced L-DOPA-induced dyskinesia in a rat model of Parkinson's disease, with dutasteride showing greater effectiveness at lower doses.
research ERRATUM
This notice corrects an article on fluridil for androgenetic alopecia, indicating potential conflicts of interest due to the authors' patent holdings and funding source; it reports no new research findings.
research Ultrastructural localization of hair keratin homologs in the claw of the lizard Anolis carolinensis
In this study, researchers found that alpha-keratin homologs similar to those in mammalian hair are present in the claws of the lizard Anolis carolinensis, suggesting a structural role during claw formation.
research Mechano-encoding hydrogel microspheres for extracellular and pericellular matrix remodeling in musculoskeletal organoids
This review focuses on hydrogel microsphere-mediated strategies to improve organoid culture by addressing deficiencies in extracellular matrix organization, potentially enhancing the physiological accuracy and clinical translatability of osteomuscular in vitro models as reported in this study.
research Presentación en el CITA de los resultados del proyecto “Estudio Integral del Cabrito Lechal Español”
This analysis examines how faculty-related Instagram accounts have adapted their posts during the recent application cycle, including showcasing credentials and incorporating new virtual engagement tools, but reports no new research findings.
research A “first” on the horizon: the expansion of uterus transplantation to transgender women
This review discusses the emerging considerations and challenges of uterus transplantation for transgender women but presents no new clinical results.
research The effects of fulvic acids and low-level laser therapy on orthodontic retention in rats
This study found that low-level laser therapy effectively reduced relapse rates, while functional appliances did not; combining them offered no additional benefits.
research The Safety and Efficacy of Macrofocused Ultrasound without Visualization on Enlarged Facial Pores among Thai Patients: A Pilot Study
This study reported that a single treatment using macrofocused ultrasound energy with a 2 mm transducer significantly reduced pore count, pore volume, and pore index in 34 Thai subjects with enlarged facial pores over a 6-month period, with no adverse events observed.
research Use of Urinary Bladder Matrix, a Bioactive, Acellular Scaffold, in Transplant Donor Scars and Androgenetic Alopecia: Initial Clinical Experience
This case series provides anecdotal evidence that urinary bladder extracellular matrix may improve hair regrowth in donor scars and enhance hair follicle graft outcomes in hair restoration surgery.
research Finasteride
research Finasteride
research Finasteride
research Enhanced ex vivo skin retention of bicalutamide using a nano-in-micro composite: Drug-loaded lipid vesicles in a dissolving microarray patch
This study developed and tested Bicalutamide-loaded lipid vesicles in dissolving microarray patches for topical application, finding that they effectively deliver Bicalutamide through murine skin while maintaining a favorable safety profile, suggesting potential to improve treatments for androgenetic alopecia.
research USE OF UPADACITINIB IN 2 CASES OF REFRACTORY SYSTEMIC LUPUS ERYTHEMATOSUS
In this case report, two female patients with refractory systemic lupus erythematosus showed significant improvement after treatment with the JAK inhibitor upadacitinib, indicating potential as a promising option for difficult cases, although further research is needed to confirm its broader safety and efficacy.
research 21 Follicular Unit Transplantation or Follicular Unit Excision: Planning andDecision-Making
This review discusses the choice between follicular unit transplantation (FUT) and follicular unit excision (FUE) in hair restoration surgery, highlighting their respective advantages and how improved techniques have increased FUE's popularity despite equivalent aesthetic results with FUT.