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5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.

Early onset hair loss linked to genetics and androgen levels.

Dermal EZH2 controls skin cell development and hair growth in mice.

Dermal EZH2 controls skin cell growth and differentiation in mice.

The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Mice lacking Insig proteins had hair growth problems due to cholesterol buildup, but this was fixed by the drug simvastatin.

Baricitinib helps treat several diseases, including COVID-19, but has side effects and needs careful monitoring.

Researchers found potential urine markers for polycystic ovary syndrome, including testosterone-glucuronide and 11α-hydroxyprogesterone, which may help diagnose the condition.

5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.

Excessive body hair in women can be caused by various conditions and treated with medication like Diane® 35 or androgen blockers.

The research identified and described a gene important for hormone conversion in endangered catfish, which varies in activity during different reproductive stages and after hormone treatment.

Ezh2 controls skin development by balancing signals for dermal and epidermal growth.

Some herbs show promise as antiandrogenic agents.

High blood pressure drugs often cause skin lupus, stopping the drug usually helps. A vaccine helps prevent genital herpes and HPV-16. More frequent light therapy clears psoriasis faster. No link was found between low iron and chronic hair loss.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Severe insulin resistance can be managed with medication, lifestyle changes, and treatment for related conditions.

Anti-IL-1 treatments might help with certain types of hair loss in people with high inflammation.

Managing metabolic syndrome needs both lifestyle changes and medical treatments.

Eating 500 fewer calories a day and making lifestyle changes can improve PCOS symptoms and reduce diabetes risk; more research is needed on its causes and treatments.

Estrogen increases blood vessel growth factor production, while testosterone blocks this increase.

Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.

Medications for PCOS don't seem to raise heart disease risk.

Metabolic syndrome's individual issues are real and need treatment to reduce diabetes and heart disease risks.

Taking riboflavin and eating less lysine can help some people with a specific genetic disorder avoid brain damage.

Compounds from the plant Mammea siamensis may help treat hair loss.

Finasteride doesn't affect erections much, but may decrease libido in men.

The document concludes that early diagnosis and treatment of PCOS in teenagers is important for managing symptoms and preventing long-term health problems.