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Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.

Oxidative stress and immune dysfunction are linked to both Hashimoto's thyroiditis and polycystic ovary syndrome, with diet and specific treatments important for managing these conditions.

PCOS starts in adolescence with hormonal issues, leading to adult health problems, and early treatment is crucial.

High-intensity interval training improves certain hormone levels and lipid profiles in women with PCOS.

Losing 5-10% body weight can improve PCOS symptoms, letrozole is better than clomiphene for fertility, and managing weight and blood sugar is important to reduce pregnancy complications.

Eating disorders can cause various hair problems, and while hair loss in these disorders is linked to metabolic syndrome, treatment focuses on specific medications and lifestyle changes for the syndrome.

People with reproductive, thyroid disorders, and type 2 diabetes can experience voice changes, but more research is needed to understand this better.

The 2023 guideline advises a detailed approach for PCOS, focusing on early detection, lifestyle and medical treatments, and managing health risks.

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

Metformin lowers prolactin in women without PCOS but not in those with PCOS, where it reduces other hormones instead.

Enobosarm significantly increased muscle mass and improved physical function in elderly men and postmenopausal women without serious side effects.

Proper nutrition can help manage PCOS symptoms and improve overall health.

People with androgenetic alopecia, both men and women, are more likely to develop heart diseases in the future.

Women with irregular periods should be checked for PCOS and treated early to prevent complications, with birth control pills helping to manage symptoms.

The article suggests renaming Polycystic Ovarian Syndrome (PCOS) to "Hyperandrogenic Persistent Ovulatory Dysfunction Syndrome" (HA-PODS) for accuracy and consistency, but no final decision was made.

Troglitazone increases subcutaneous fat in lipodystrophy patients.

Menopausal acne is treated with medications and lifestyle changes, but careful choice is needed due to side effects.

Orlistat helped reduce weight and testosterone in obese women with PCOS but did not significantly affect other androgens or cholesterol levels.

Late diagnosis of congenital adrenal hyperplasia can greatly affect physical development, gender identity, and sexual health.

The document concludes that hirsutism can be managed with various treatments tailored to the individual, potentially improving quality of life.

Older, overweight women with children and a family history of hair loss are more likely to experience female pattern hair loss.

Hormonal imbalances can cause hair loss, and understanding them can help develop better treatments.

Using rodents for research shows that health problems in the womb can cause diseases later in life.

Microneedles are promising for long-acting drug delivery and can improve patient compliance, but more data is needed to confirm their effectiveness.

Retinoic acid affects male and female muscle energy use and function differently.

Multi-omics techniques help understand the molecular causes of androgenetic alopecia.

Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.

Phytotherapeutic compounds and supplements can help manage Polycystic Ovarian Syndrome (PCOS).

Chromium picolinate was better tolerated than metformin for PCOS with fewer side effects.

Metformin should be used for PCOS mainly in those with glucose intolerance, and has limited benefits for infertility or hirsutism.