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Gene variant linked to prostate cancer, hormone levels, and hair loss.

Finasteride poorly inhibits type 1 5AR, affecting its effectiveness.

Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.

Men with Type 2 Diabetes have lower DHT levels, which may affect fertility and lipid profiles.

New compounds were made that effectively block enzymes related to prostate issues and hair loss.

Insulin resistance is linked to high male hormone levels in women, often seen in those with PCOS.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Hair loss linked to metabolic issues and insulin resistance; early assessment may reduce future health risks.

Ovarian SAHA syndrome makes women with PCOS more resistant to insulin and increases their risk of blood sugar problems.

FCE 28260 is a stronger and longer-lasting inhibitor of 5α-reductase than finasteride, which may make it a better treatment for certain medical conditions.

Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.

Male yak hair growth is influenced by DHT synthesis, which is promoted by 5α-red1 and AR during growth phases, while E2 may inhibit growth through ERα.

Finasteride affects the male rat brain by reducing certain protein activation, but these effects may reverse after stopping the drug.

Low testosterone does not prevent prostate cancer in men with type 1 diabetes.

The article suggests renaming Polycystic Ovarian Syndrome (PCOS) to "Hyperandrogenic Persistent Ovulatory Dysfunction Syndrome" (HA-PODS) for accuracy and consistency, but no final decision was made.

Finasteride, a drug used for certain conditions, can cause serious side effects like sexual dysfunction, suicidal thoughts, and increased diabetes risk, and there's a need for more awareness and research about these effects.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

Finasteride effectively reduces hair loss by decreasing androgen levels.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.

The document concludes that managing PCOS involves treating symptoms and reducing long-term metabolic risks, with lifestyle changes being important.

The document concludes that accurate diagnosis and management of PCOS are crucial due to its associated health risks.

Dicentrine reduced heart disease risk factors in rats, T-588 protected mice brains without side effects, Provir blocked herpes virus and lessened mouse symptoms, and LY191704 could treat hair loss and prostate issues.

Men with early balding showed higher levels of certain genes linked to hair loss and possibly prostate cancer.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

PCOS is a hormonal disorder causing symptoms like irregular periods and acne, and increases the risk of diabetes and heart disease.

PCOS is a complex disorder in women that can lead to various health risks and requires personalized treatment.

PCOS affects fertility and is linked to obesity and menstrual irregularities; lifestyle changes are recommended for treatment.