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Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.

Two siblings with a rare type of rickets and hair loss had low vitamin D levels, which is not typical for their condition.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Plant-based products can improve hair and skin health without harmful side effects.

Overexpressing thrombospondin-1 in mice skin prevents UVB-induced skin damage.

Blood pressure drugs can cause skin lupus, early treatment is key for baby herpes and diabetic foot ulcers, a certain vaccine works against genital herpes and HPV in women, more frequent light therapy helps psoriasis, smoking and drinking can worsen psoriasis, a cream clears up a type of skin cancer, and low iron levels don't cause chronic hair loss.

Astilbin can potentially calm overactive immune responses, like in Type 1 Diabetes, by suppressing certain cell activities and reducing inflammation.

A brain-produced steroid causes increased scratching in mice with a skin condition similar to eczema.

Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Sebocytes play a key role in controlling androgen levels in human skin.

5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.

Insulin resistance is linked to high male hormone levels in women, often seen in those with PCOS.

Mutations in certain receptors can cause diseases and offer new treatment options.

Aging scalp skin contributes to hair aging and loss, and more research is needed to develop better hair loss treatments.

Vitamin D and estrogen may help protect heart and kidney health, and maintaining sufficient vitamin D levels could be especially beneficial for African Americans, postmenopausal women, and people with chronic kidney disease.

Saw palmetto extract can block the enzyme that converts testosterone in pig prostate cells.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Gypenosides from Gynostemma pentaphyllum were found to have anti-aging effects, increasing skin collagen and reducing wrinkles.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

Lysophosphatidic acid is important for skin health and disease, and could be a target for new skin disorder treatments.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

Lung repair involves both dedicated and flexible stem cells, important for developing new treatments.

Androgens can both promote and prevent hair growth due to differences in gene expression in hair follicles.

Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.

The CRH/CRH-R1 system might be involved in causing lichen planus.

Thyroid disease can cause hair loss and treating thyroid problems might help with hair disorders.