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Alisertib was found to be an effective and tolerable treatment for children with recurrent brain tumors.

The topical inhibitor CUR61414 was not effective in treating basal cell carcinoma in human trials.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

Scientists have created a new hair loss treatment using ultrasound to deliver gene-editing particles, which resulted in up to 90% hair regrowth in mice.

Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.

Extramammary Paget disease can spread deeply into tissues, reaching up to 3.6 mm.

LPA3 is crucial for embryo implantation and links LPA to prostaglandin signaling.

Thymosin β4 helps improve skin healing and reduce scarring.

CRTH2 antagonists might be useful for treating many conditions because they play a role in immune and inflammation responses.

African American men with prostate cancer have more androgen receptor mutations, which may lead to more aggressive cancer compared to Caucasian American men.

The cause of atypical Cushing's syndrome in dogs, possibly linked to sex hormones, is not yet proven.

Interferons are effective for some skin conditions and cancers, but can have side effects and need more research for optimal use.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Genetic factors alone might not cause pemphigus vulgaris; other factors like birth complications and puberty may trigger it.

Japan improved its regulation of regenerative medicine to ensure safety and prevent unproven treatments.

Both human and animal-derived small extracellular vesicles speed up skin healing equally well.

The document concludes that pregnancy and cancer share immune evasion tactics, but more research is needed before using checkpoint blockade immunotherapy in pregnant cancer patients to avoid harm to the placenta.

The document concludes that side effects from Smoothened inhibitor drugs for skin cancer are reversible and can be managed with a team approach to maintain quality of life.

New patents show progress in developing drugs targeting the Wnt pathway for diseases like cancer and hair loss.

AHCC reduces hair loss and liver injury caused by chemotherapy in rodents.

Skin reactions to drugs are common and can be deadly, usually requiring stopping the drug and may be better prevented with genetic testing in the future.

Boron neutron capture therapy for head and neck cancer can cause side effects like mouth sores and skin irritation, which vary depending on where the treatment is aimed.

Nanotechnology is improving drug delivery and targeting, with promising applications in cancer treatment, gene therapy, and cosmetics, but challenges remain in ensuring precise delivery and safety.

Apoptosis may contribute to hair loss in androgenetic alopecia.

New probes were created to effectively measure specific enzymes involved in fat metabolism, which could help develop new drugs.

The document concludes that individualized treatment for malignant epithelial tumors is necessary and more research on metastatic squamous cell carcinoma treatments is needed.

MSC-Exos can aid organ development and offer therapeutic benefits for various conditions.

The document describes various skin conditions, their features, and treatments but lacks detailed study size information.

Cinnamon bark extract may help prevent weight loss and hair loss in breast cancer patients during chemotherapy and is safe to use.