20 citations
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June 1995 in “Tetrahedron Letters” This study reported that newly synthesized phenanthridin-3-one derivatives effectively inhibit human steroid 5-α-reductase.
12 citations
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August 2016 in “Mycopathologia” This case study reports a 36-year-old man's fungal infection, identified as Trichosporon inkin, which was treated with shaving and antifungal therapy.
July 2026 in “International Journal of Molecular Medicine” In this study, cepharanthine showed potent antiviral effects against tick-borne encephalitis virus in vitro by reducing viral replication and inflammation in human lung and neuroblastoma cells.
7 citations
,
January 2022 in “Anais Da Academia Brasileira De Ciencias” This study found that essential oils from Hedychium spicatum showed anti-inflammatory, antinociceptive, antipyretic, and antioxidant activities, with site-specific variations in their effectiveness.
86 citations
,
January 2019 in “Frontiers in Immunology” The document concludes that diagnosing and treating Human African Trypanosomiasis is challenging, but new treatments like fexinidazole are promising.
5 citations
,
September 2014 in “Journal of Pharmaceutical Sciences” 25 citations
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September 1973 in “Archives of dermatology” In this study, a daily topical application of a 0.05% tretinoin solution effectively removed dark plugs and resolved symptoms of trichostasis spinulosa.
31 citations
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September 2014 in “International Journal of Dermatology” This article reviews anthralin's pharmacology, mode of action, and its use for psoriasis and other dermatoses, but reports no new clinical results.
This study identified ALDH1A1 as a regulator of melanogenesis and suggests its inhibition, through agents like cyanamide, may be a promising therapeutic approach for treating hyperpigmentation disorders such as melasma.
January 2025 in “Journal of the European Academy of Dermatology and Venereology” This study highlights that Trichophyton mentagrophytes genotype VII, primarily transmitted sexually among men who have sex with men, has established itself in Europe, necessitating awareness and surveillance to prevent its spread.
6 citations
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August 2004 in “Journal of Chemical Information and Computer Sciences” This study found that certain molecular quantum descriptors can be directly correlated with the biological activity of benzo[c]quinolizin-3-ones, potentially aiding in the identification and design of active compounds.
6 citations
,
December 2020 in “Biological & Pharmaceutical Bulletin” This study found that certain fatty acids and triterpenoid-glycosides from Eclipta prostrata L. leaves exhibit potent inhibitory effects on the protein tyrosine phosphatase 1B enzyme, suggesting potential anti-diabetic and anti-obesity benefits.
6 citations
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September 2015 in “Journal of Medicinal Chemistry” This study synthesized and verified the structures of Setipiprant's major and minor metabolites, confirming their regio- and enantioselectivity from earlier proposals in a clinical study.
September 2019 in “Asian Journal of Pharmaceutical and Clinical Research” In this study, researchers found that the methanolic seed extract of Tectona grandis, known for its use in traditional medicine, demonstrated strong analgesic properties in Swiss albino mice, being effective at doses of 200–250 mg/kg and safe up to 1000 mg/kg.
4 citations
,
December 2024 in “International Journal of Molecular Sciences” This study found that extracts from Hom Thong banana peels, rich in phenolic compounds, may inhibit melanin production in human and mouse melanoma cells, showing potential as anti-melanogenic agents comparable to standard treatments like arbutin and kojic acid.
6 citations
,
October 1998 in “PubMed” This case study reports a new variant of chronic dermatophytosis with giant cutaneous horns, suggesting a possible genetic link and highlighting successful treatment with antifungal medications.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study formulated and evaluated a polyherbal hair dye using Phyllanthus reticulatus fruit and other natural ingredients, reporting that the dye provided satisfactory color, stability, scalp pH compatibility, and did not cause irritation, also demonstrating antioxidant and antimicrobial properties that benefit scalp health.
September 2021 in “CRC Press eBooks” This article discusses trichotillomania and trichoteiromania, focusing on their clinical presentation, main trichoscopic features, and similarities in hair loss patterns but reports no new research findings.
180 citations
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November 1991 in “American Journal of Psychiatry” This study found that fluoxetine did not demonstrate short-term efficacy in treating trichotillomania in a placebo-controlled, double-blind crossover setting.
5 citations
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November 2010 in “Veterinary Record” Treatment with oral terbinafine and topical enilconazole was successful in resolving a Trichophyton dermatophytosis outbreak in L'Hoest's monkeys, with complete mycological cure achieved after eight weeks.
1 citations
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September 2025 in “Pediatric Dermatology” This systematic review reported that habit reversal training showed the most consistent benefit for treating pediatric trichotillomania, while evidence for pharmacological treatments and alternative therapies like N-acetylcysteine remains insufficient, highlighting the need for early behavioral intervention and further research into standardized treatment protocols.
April 2022 in “Molecules” This study identified two potent 5α-reductase inhibitors from Tectona grandis leaves, and suggests that ethanol is a preferable solvent for extracting these compounds, which are potential ingredients for hair loss treatments.
234 citations
,
November 2009 in “American journal of human genetics” This study identified genetic variants in the Trichohyalin gene that account for approximately 6% of the variance in hair morphology among Australians of European descent.
35 citations
,
September 2012 in “PloS one” This study found that in Arabidopsis seedlings, tonoplast intrinsic proteins are targeted to the vacuole via at least two pathways, including pathways with differing sensitivity to a chemical inhibitor that affect root hair growth and PIN2 targeting.
1 citations
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July 2022 in “Plant Cell, Tissue and Organ Culture (PCTOC)” This study identified that the biosynthetic pathways for coumestans in Eclipta prostrata are derived from acetate and shikimate pathways, while phenylpropanoid biosynthesis is exclusively from the shikimate pathway.
32 citations
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January 2000 in “Human Heredity” This study found that the mutation Glu402Lys in keratin hHb6 may be associated with monilethrix, and homozygous patients in a consanguineous family exhibited more severe symptoms.
This study demonstrates that the trichohyalin gene is located at chromosomal region 1q21, where several other genes related to epidermal differentiation also map.
138 citations
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November 1977 in “Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics” 111 citations
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April 2000 in “British journal of dermatology/British journal of dermatology, Supplement” In this study, physiological levels of free T3 significantly enhanced the survival of human hair follicles in vitro.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” In a laboratory setting, this study found that Biotrinine® dry extract activated hair follicle growth pathways and increased certain growth factor secretions in human dermal papilla cells, suggesting potential benefits for treating chronic hair loss.