83 citations
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January 2001 in “American journal of clinical dermatology” This review discusses the clinical features of trichotillomania and the challenges in its diagnosis and treatment, reporting no new clinical findings while highlighting the need for specialized therapy and better therapeutic options.
June 2024 in “Korean Journal of Pharmacognosy” This study found that taxifolin glycosides isolated from Rhododendron mucronulatum showed promise for developing treatments for male pattern hair loss by inhibiting DHT production and enhancing hair growth-promoting factors.
72 citations
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May 1993 in “The Journal of Cell Biology” This study detailed the structure and amino acid composition of sheep trichohyalin, noting its presence in various tissues and suggesting a possible functional role beyond structural support in hair follicles.
1 citations
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December 2014 in “Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology” This study reports that a 15-year-old with trichotillomania showed improvement with aripiprazole treatment, though no consensus on treatment exists in the literature.
November 2024 in “Actas Dermo-Sifiliográficas” This review outlines current treatment strategies for trichotillomania, noting that while cognitive-behavioral therapy is effective, N-acetylcysteine and memantine are also recommended due to their safety and efficacy, though evidence for other drugs like fluoxetine and naltrexone remains limited.
In this laboratory study, the methanolic extract of Eclipta alba demonstrated significant anthelmintic activity against earthworms (Pheretima posthuma), causing paralysis and death at doses of 50-100 mg/ml, with stronger effects observed at higher concentrations compared to the standard treatment, albendazole.
4 citations
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January 2023 in “Skin Pharmacology and Physiology” This study observed that an ointment containing pine turpentine oil, larch turpentine, and eucalyptus oil showed significant improvement over placebo in lesion evolution, responder rates, and patient assessments for treating acute folliculitis, while being well-tolerated across treatments.
27 citations
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October 2002 in “International Journal of Dermatology” This study presents a microscopic analysis of the pruritic variant of trichostasis spinulosa in two patients and reviews existing literature, reporting no new clinical results.
February 2019 in “Journal of the Faculty of Agriculture Kyushu University” This study found that terpene compound concentrations in coniferous tree leaves were generally highest in spring and summer, suggesting these seasons are most effective for extracting essential oils.
January 2018 in “Our Dermatology Online” This case report describes a carpenter who presented with contact dermatitis and trichopathy with whitish nodules in the axillary hair.
August 2025 in “International Journal of Molecular Sciences” This study found that arginine vasotocin is evolutionarily conserved across diverse taxa and may play roles in neuroendocrine, immune, and stress signaling, with potential antimicrobial applications.
142 citations
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November 2009 in “BMC Complementary and Alternative Medicine” This study supports the traditional use of T. procumbens for diabetes treatment, showing improvements in body weight and glucose tolerance with no toxicity signs in normal rats.
10 citations
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February 1993 in “International Journal of Cosmetic Science” This study found that clove, olive, and turpentine oils completely prevented hair penetration by the fungi Microsporum gypseum and Trichophyton vanbreuseghemii.
4 citations
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August 2018 in “International Journal of Current Microbiology and Applied Sciences” This study identified various phytochemicals and compounds in Eclipta prostrata leaves using qualitative tests, FTIR, and GC-MS analysis, highlighting the presence of phytol and squalene among others.
September 2025 in “Animals” In this study, dermatophytosis was prevalent among 52% of dogs and 70% of cats with skin lesions, with younger animals facing higher infection risks; combined itraconazole, clotrimazole, supportive care, and vaccination led to the fastest recovery.
This study purified trichohyalin protein from pig tongue epithelium, characterizing its unique properties and structure, which may facilitate future functional research.
27 citations
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August 2017 in “Anais Brasileiros de Dermatologia” In this case report, a patient with trichotillomania showed a significant positive response to treatment with N-acetylcysteine, suggesting its potential effectiveness for this disorder according to the authors’ observations.
This study on Antirrhinum trichomes found that stickiness in A. hispanicum is due to a recessive allele and mapped it to a specific region on Chromosome 1, while baldness in A. siculum likely involves a novel hairy allele.
1 citations
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December 2022 in “Journal of applied biological chemistry” This study found that TRP-hair essence significantly protected and improved the quality of human hair, particularly against heat stress, by enhancing cuticle health and maintaining hair color.
3 citations
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September 1973 in “Archives of dermatology” This study reports that daily topical application of a 0.05% tretinoin solution can eliminate the hair plugs and symptoms associated with trichostasis spinulosa.
June 2023 in “CHEDS Journal of Chemistry Education and Science” In this experimental study, researchers developed a hair tonic using green spinach leaves and assessed its feasibility based on vitamin content and sensory characteristics, finding that the tonic was generally liked by panelists in hedonic tests.
2 citations
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August 2007 in “Zoonoses and Public Health” This study documented clinical cases of dermatophytosis in two free-ranging southern chamois in the Eastern Pyrenees, with Trichophyton mentagrophytes identified in both animals.
31 citations
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February 2007 in “Journal of Structural Biology” Oxidation changes the structure of hair protein filaments, causing them to compact and rearrange.
1 citations
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March 2013 in “Clinical, cosmetic and investigational dermatology” This case report details an eleven-year-old male with recurring alopecia initially attributed to fungal infections but ultimately diagnosed as trichotillomania.
71 citations
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May 2006 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, researchers found that trichothiodystrophy hair brittleness is linked to abnormalities in sulfur content and structural organization, making it prone to breakage.
2 citations
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December 2020 in “American Journal of Dermatological Research and Reviews” This study found that combining 308-excimer phototherapy with intramuscular triamcinolone acetonide was effective and well tolerated for treating resistant alopecia totalis, showing a 90% overall response rate in the ten patients studied, with the best results observed in younger patients.
48 citations
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May 1991 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that trichohyalin, a protein previously thought to be restricted to hair and tongue, is also present in isolated cells within the granular layer and stratum corneum of normal human epidermis.
14 citations
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January 2020 in “Evidence-based Complementary and Alternative Medicine” This study found that a newly synthesized peptide from fermented Trapa japonica extract significantly promoted wound recovery and showed antiaging effects in skin cells and a clinical study, suggesting potential as a cosmetic product.
6 citations
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January 2011 in “European Journal of Dermatology” This article discusses monilethrix, a rare human hair dysplasia caused by mutations in hair keratins, but reports no new clinical findings.
July 2025 in “Scientific Reports” This study observed that serotonin signaling promoted hair shaft elongation and upregulated hair growth-related genes in dermal papilla cells, suggesting its potential role in advancing alopecia therapy.