Molecular Diagnostics and Control of Zoonotic Dermatophytosis: First Detection of Trichophyton Indotineae in a Dog in Africa

    September 2025 in “ Animals
    Hend Adel Zineldar, Wafaa M. El-Neshwy, Romeo Teodor Cristina, Nasser Z. Abouzeid, Mohammed Ibrahim Eisa, Флорин Муселин, Eugenia Dumitrescu, Adel Abdelkhalek, Yasmine H. Tartor
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    Studysummary In this study, dermatophytosis was prevalent among 52% of dogs and 70% of cats with skin lesions, with younger animals facing higher infection risks; combined itraconazole, clotrimazole, supportive care, and vaccination led to the fastest recovery. Our plain-language summary of this paper — not a Tressless recommendation.
    This study highlights the first detection of Trichophyton indotineae in a dog in Africa, emphasizing the zoonotic risks of dermatophytosis in pets, particularly dogs and cats. Conducted on 140 animals, it found Microsporum canis as the most prevalent infection cause. Younger animals and housing conditions were significant risk factors. The study evaluated treatment regimens, finding that a combination of itraconazole, clotrimazole, supportive therapy, and a dermatophyte vaccine was most effective, achieving rapid clinical improvement. The research underscores the importance of accurate diagnosis, effective treatment, and ongoing surveillance to manage dermatophytosis and prevent zoonotic transmission.
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