27 citations
,
June 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified numerous size polymorphisms in the human ultrahigh sulfur KAP4 genes due to intragenic sequence variations, suggesting these polymorphisms may have arisen through deletions and duplications during evolution.
2 citations
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January 2014 in “Hair therapy & transplantation” This review explores the molecular controls of hair follicle cycling and highlights the challenge of developing effective treatments for common hair disorders without providing new clinical results.
November 2022 in “Research Square (Research Square)” This study found that keratin-associated proteins related to metallothionein and occludin appear in various animals, suggesting they may have roles beyond hair characteristics and were later adapted for hair production.
September 2021 in “Mağallaẗ al-Muẖtar li-l-ʿulūm” This report describes a case of two sisters with kinky, tangled hair diagnosed using trichoscopic and microscopic methods; they were treated with topical minoxidil.
5 citations
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January 2024 in “Science Advances” In this study, researchers identified Tenascin-C as a marker for touch dome keratinocytes, which maintain themselves and can develop into Merkel cells following injury, showing they share molecular traits with various epidermal keratinocytes.
4 citations
,
January 2017 in “Journal of veterinary medical science” This report diagnosed a mass below a dog's eye as desmoplastic tricholemmoma based on histopathological and immunohistochemical findings.
1 citations
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January 2018 in “Indian journal of dermatopathology and diagnostic dermatology” This review discusses the use of trichoscopy as a valuable diagnostic and prognostic tool for various hair and scalp disorders, reporting no new clinical results.
38 citations
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January 2016 in “Indian Journal of Dermatology, Venereology and Leprology” This study found that trichoscopy was useful in diagnosing different types of alopecia, with specific trichoscopic features aiding in the differential diagnosis.
6 citations
,
June 1976 in “Journal of ultrastructure research” This study identified the presence of recognizable organelles, such as lysosomes and mitochondria, in both the keratinized fiber and the hardened inner root sheath of the Romney wool follicle.
28 citations
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August 2018 in “Dermatologic Clinics” This article discusses various aspects of trichoscopy for diagnosing hair and scalp disorders and reports no clinical results, offering guidance and highlighting pitfalls for better application of this tool by dermatologists.
1 citations
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January 2022 in “Clinical dermatology review” This case report describes a 26-year-old male patient with trichofolliculoma, highlighting dermoscopic features that aid its diagnosis and distinct characteristics from other similar lesions.
April 2023 in “Our Dermatology Online” Trichoscopy is effective in diagnosing trichotillomania by showing specific hair patterns.
November 2021 in “Skin appendage disorders” This case report describes the first known instances of male androgenetic alopecia with trichoteiromania, suggesting self-induced hair loss can occur alongside patterned miniaturization of hair.
January 2021 in “International journal of dermatology, venereology and leprosy sciences” This study found that trichoscopy is a valuable diagnostic tool for identifying hair loss patterns in women and can help avoid scalp biopsies in unclear cases.
September 2022 in “TURKDERM” This article reports an unprecedented case of trichofolliculoma in the gluteal area, previously unreported in English literature.
8 citations
,
March 2011 in “Archives of Dermatology” This study suggests that corkscrew hair could serve as a new diagnostic marker for tinea capitis and that dermoscopy might help diagnose atypical cases swiftly.
9 citations
,
January 2012 in “International journal of trichology” This case report suggests that Trichostasis spinulosa should be considered in diagnosing treatment-resistant open comedone-like lesions and that skin surface biopsy might be an effective diagnostic method.
89 citations
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March 2018 in “The Journal of Dermatology” This review presents various trichoscopic findings for diagnosing alopecia areata but reports no new clinical results, emphasizing that no single marker is pathognomonic and multiple features should be considered together.
September 2023 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, researchers examined trichoscopic features in 80 patients with androgenetic alopecia and found that hairshaft thickness heterogeneity was the most common feature, highlighting trichoscopy as a useful, non-invasive diagnostic tool for assessing this condition.
175 citations
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December 1980 in “Archives of Dermatology” In this study, researchers examined two new cases of trichothiodystrophy and observed that the condition is linked to decreased synthesis of high-sulfur matrix proteins in hair.
June 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that fibrosis-associated trochanters in central centrifugal cicatricial alopecia are enriched with hair follicle stem cells and may indicate a disrupted stem cell niche contributing to scarring.
26 citations
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January 1993 in “Dermatology” This report describes a new case of isolated trichothiodystrophy with characteristic brittle hair and suggests a simplified classification scheme for understanding sulfur-deficient hair disorders.
99 citations
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May 1998 in “Journal of biological chemistry/The Journal of biological chemistry” This study found that small proline-rich proteins modify the biomechanical properties of cornified cell envelopes in rodent forestomachs, potentially affecting the tissue's ability to withstand mechanical stress.
June 2021 in “Scholars journal of applied medical sciences” This article reviews the literature on trichofolliculoma, a rare benign hair follicle tumor, and provides an observational report, noting the lack of consensus on treatment.
January 2007 in “Revista del Centro Dermatológico Pascua” This case report describes a 2-year-old boy diagnosed with trichothiodystrophy, characterized by fragile hair, intellectual damage, diminished fertility, and short stature.
August 2025 in “Skin Appendage Disorders” This case study observed that in a child with spontaneous trichonodosis, topical minoxidil and gentle hair care improved hair length and strength over two years, suggesting a potential genetic predisposition for the disorder.
13 citations
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June 2012 in “Journal of Dermatological Case Reports” This report describes an 8-year-old male with trichotillomania, confirmed by trichoscopy showing characteristic hair damage and patterns.
January 2019 in “The Egyptian Journal of Hospital Medicine” In this study, researchers evaluated trichoscopic features in 500 Egyptian patients with patchy hair loss and found specific patterns, such as perifollicular scale with 90% sensitivity and 99.5% specificity, which effectively aid in diagnosing primary cicatricial alopecias.
January 2016 in “Journal of Clinical Dermatology” This study found that trichoscopy is useful for diagnosing androgenetic alopecia and alopecia areata, and the severity of androgenetic alopecia can be assessed with this method.
7 citations
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August 2022 in “Nature communications” This study found that Thy1+ keratinocytes in the basal layer of the interfollicular epidermis play a crucial role in epidermal homeostasis and wound repair, with their ablation impairing these processes.