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Pediatric dermatologists need to understand the unique skin health needs of LGBTQIA youth to provide better care.

Younger transgender women have surgery earlier, are mostly attracted to men, and show more preoperative depression that improves after surgery compared to older transgender women.

The safety and effectiveness of gender-affirming treatments for children are uncertain, with potential long-term risks like infertility.

Hormone therapy affects hair growth in transgender individuals, with testosterone potentially causing hair loss in trans men and estrogen reducing facial/body hair in trans women; treatment options vary.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

Finasteride effectively treats hair loss in transgender men with few side effects.

Oral estradiol works for many transgender women but needs personalized dosing and monitoring.

Hormone therapy in transgender individuals can increase acne and affect hair growth and loss.

Some antiandrogens may lower testosterone better than others, but it's unclear which is best for feminization in transgender women; more research is needed.

Testosterone pellets might work for transgender men's hormone therapy, but more research is needed.

Injectables can feminize or masculinize a transgender person's face, but more research is needed for best practices.

Orthognathic surgeons play a key role in modifying masculine facial features to be more feminine, often improving transgender women's quality of life.

Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.

Gender-affirming hormone therapy improves physical performance in trans men to the level of cisgender men, while in trans women, it increases fat mass and decreases muscle mass, with no advantage in physical performance after 2 years.

Facial feminization surgery helps make facial features more feminine, improving patient satisfaction and safety.

AGA treatments like minoxidil and LLLLT are safe and effective for gender minority patients.

Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.

Ginseng and Albizia extracts help prevent hair thinning with age.

Skin can become dry and thick in hypothyroidism.

Inclusive and culturally competent healthcare is crucial for transgender and non-binary individuals.

Parental support and gender-affirming care are crucial for the mental health of transgender adolescents.

Testosterone treatment in transgender teens can worsen acne, requiring careful treatment due to mental health and medication side effects.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Hair transplants are effective for some women and many male-to-female transgender patients if done carefully by an experienced team.

The document concludes that more inclusive research involving the transgender community is needed, especially on the neovaginal microbiome of trans women.

Transmasculine individuals on testosterone therapy need tailored contraception and fertility advice due to unique risks and benefits of each contraceptive method.

Hair transplantation can help transgender patients affirm their gender identity.

Doctors are preparing to potentially perform uterus transplants in transgender women, considering technical, hormonal, and ethical factors.

Transgender and gender diverse youth often have skin issues like acne and scarring, but few get referred to dermatologists.

Dermatologists are essential in helping transgender and gender diverse patients with skin and hair issues related to gender affirmation and hormone therapy.