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Regulating certain sex hormones may help delay facial aging.

Testosterone therapy can improve sexual function in women but long-term safety is unclear.

Men and women experience skin aging differently due to changes in sex hormone levels with age.

Estrogen-progestin contraception lowers ovarian, endometrial, and colon cancer risk but may raise breast and cervical cancer risk, helps with menstrual and acne issues, and new methods are as effective as pills. Metformin helps overweight women with PCOS and insulin resistance, and dopamine agonists treat prolactinomas.

Using β-cyclodextrin derivatives improves the solubility and bioavailability of steroidal drugs.

Testosterone Replacement Therapy can improve sexual health in postmenopausal women with low sexual desire, but more research is needed on its long-term effects.

The runner's bone injuries were linked to untreated Celiac Disease and low energy availability affecting her bone density.

Polymers increased skin permeation and stability of steroid hormones in liposomal formulations.

A woman's virilization symptoms were caused by her partner's use of testosterone cream, which resolved after they separated.

Testosterone increases hair testosterone levels, stress raises hair cortisol, and relationship status affects hormone levels.

Testosterone in older women can increase bone density, muscle mass, fat mass, improve memory, and boost libido, but may cause nipple color changes.

The combined treatment for hair loss is effective, easy to use, and has mild side effects.

Women have unique stroke risks due to hormones, contraceptives, pregnancy, and menopause.

DHT is a strong androgen that may pose less risk to the prostate compared to testosterone.

A 15-year-old girl with no menstrual period was diagnosed with a genetic condition that makes her body unable to respond to male hormones, leading to female characteristics despite having male genetic makeup.

Testosterone replacement therapy helps manage deficiency and has various methods, but requires careful monitoring to avoid side effects.

Hormone treatment for transsexual individuals is effective but carries risks like thromboembolic events and mood changes, with most side effects being minor and reversible.

Transfollicular drug delivery is promising but needs more research to improve and understand it better.

Different factors like pH, gel type, and chemical enhancers affect how well hydrocortisone gets into hair follicles, and less hydrated skin doesn't work well with the test method.

Short-term testosterone therapy in women seems safe with few mild side effects, but long-term effects need more research.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Ethanol pretreatment affects drug penetration through skin and hair follicles.

Invasomes effectively deliver drugs through the skin and have potential for improved treatments.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Androgen replacement therapy can improve libido and mood in women with severe androgen deficiency, but more research is needed on its long-term safety.

Testosterone therapy increases bone density in older men with low testosterone levels.

Hair follicles may soon be used more for targeted and systemic drug delivery.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Testosterone treatment in trans men increases body and facial hair and may lead to hair loss over time, but severe skin issues are rare.

Drospirenone is a unique progestin with anti-water retention and potential blood pressure benefits, used in birth control and hormone therapy.