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Sex hormones like estrogen and testosterone may affect COVID-19 severity differently in men and women, potentially influencing prevention and treatment strategies.

Topical oligonucleotide therapy targets hair follicles effectively.

Proactive monitoring and management are essential to maximize the benefits of Trastuzumab Deruxtecan while minimizing serious side effects.

Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.

The document concludes that proper diagnosis and combined treatments are key for hirsutism management, and weight loss may help overweight patients.

Testosterone therapy may slightly increase sexual desire in women with HSDD but lacks broad recommendation due to safety concerns and limited approval.

Nandrolone might increase muscle mass with fewer side effects than testosterone but could cause erectile dysfunction and needs more research.

Tea, especially green tea, shows promise in cosmetics for skin and hair benefits but more research is needed for effective use.

Nano-sized lipid particles increase dexamethasone's skin penetration and create a reservoir in the skin layers.

The safety and effectiveness of gender-affirming treatments for children are uncertain, with potential long-term risks like infertility.

Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.

Cell transplantation faces challenges in genitourinary reconstruction, but alternative tissue sources and microencapsulation show promise.

Iontophoresis improves minoxidil delivery for alopecia treatment.

Bitter melon extract may help prevent hair loss and can be used in cosmetic products.

Finasteride microspheres help reduce hair loss for up to eight weeks with fewer side effects.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

PCOS is a genetic disorder affecting women's reproductive health, with treatments focused on symptoms like insulin resistance and fertility.

Hormone therapy may increase migraines in transgender women and decrease them in transgender men; more research is needed on migraine management in transgender individuals.

Birth control pills change the activity of certain inflammation and blood clotting genes in women with PCOS.

Vesicular carriers like liposomes may improve cosmetic skin treatment delivery and effectiveness but need more human research.

Hormonal therapy changes skin and hair in transgender patients, who need better researched dermatologic care.

Menthol boosts the hair growth effects of Phyllanthus niruri gel.

The new "differential stripping" method effectively measures how much substance gets into hair follicles.

New treatments for low male hormones improved sexual function and mood but had unclear risks, especially for older men.

Many women experience sexual dysfunction, but few seek help, and better treatment and medical training are needed.

Hair follicles could be used for targeted drug delivery, with liposomal systems showing promise for this method.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Topical nitroglycerin spray effectively prevents scalp necrosis in hair transplant patients.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.