research Characterization of the Promoter Regions of Two Sheep Keratin-Associated Protein Genes for Hair Cortex-Specific Expression
The KRTAP11-1 gene promoter is crucial for specific expression in sheep wool cortex.
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600-630 / 1000+ resultsresearch Inflammatory Role of Sex Steroids in Hidradenitis Suppurativa: An Androgenic Phenotype
Sex hormones may be linked to inflammation in Hidradenitis Suppurativa.
research Novel Progestogenic Androgens for Male Contraception: Design, Synthesis, and Activity of C7 Alpha-Substituted Testosterone
New testosterone analogs show promise for male contraception with better activity and potentially fewer side effects.
research Stat3 Partly Inhibits Cell Proliferation Via Direct Negative Regulation of FST Gene Expression
The protein STAT3 slows down cell growth by blocking the FST gene, which affects hair development in sheep.
research MOF-Mediated Histone H4 Lysine 16 Acetylation Governs Mitochondrial and Ciliary Functions by Controlling Gene Promoters
MOF controls key genes for skin development by regulating mitochondrial and ciliary functions.
research The Human Papillomavirus Type 11 Upstream Regulatory Region Triggers Hair-Follicle-Specific Gene Expression in Transgenic Mice
The HPV type 11 region activates hair-specific gene expression in mice.
research Anagen Hair Follicles Transplanted Into Mature Human Scars Remodel Fibrotic Tissue
Transplanting growing hair follicles into scars can help regenerate and improve scar tissue.
research Phase I/IIa Clinical Trial for the Treatment of Androgenetic Alopecia Using Intradermal Injections of Cultured Autologous Dermal Sheath Cup Cells
Injections of special skin cells showed potential in treating hair loss, with some participants experiencing increased hair density.
research Thermal Imaging and Trichoscopy for Detecting Inflammation in Frontal Fibrosing Alopecia
Thermal imaging is a useful non-invasive method to diagnose active inflammation in frontal fibrosing alopecia.
research Single Cell Transcriptome Profiling of Human Interfollicular Epidermis Reveals Robust Heterogeneity and Divergent Differentiation Lineages
The human skin's outer layer has more variety in cell types and development paths than previously thought.
research A Subpopulation of Itch-Sensing Neurons Marked by Ret and Somatostatin Expression
Scientists found a specific group of itch-sensing nerve cells in mice important for feeling itch but not for sensing heat or touch.
research Understanding the Role of Glycogen Metabolism in Human Hair Follicle Biology
Glycogen metabolism is important for energy and processes in human hair follicles, and hair follicles may produce glucose from lactate.
research Mapping Penetration of Cosmetic Compounds into Hair Fibers Using Time-of-Flight Secondary Ion Mass Spectrometry (TOF-SIMS)
Different oils penetrate hair differently; monounsaturated oils like olive oil penetrate better than polyunsaturated oils.
research Piperine Reduces Hair Oiliness by Inhibiting Adipogenesis of Hair Stem Cells
Piperine from black pepper can make hair less oily by blocking fat cell development in hair roots.
research Neurotrophin-4 Modulates the Mechanotransducer Cav3.2 T-Type Calcium Current in Mice Down-Hair Neurons
Neurotrophin-4 increases calcium current in specific mouse neurons through the PI3K pathway.
research Comparative Gene Expression Profiling of Senescent and Androgenetic Alopecia Using Microarray Analysis
SA linked to mitochondrial issues and oxidative stress, while AGA involves disrupted hair growth genes.
research Mapping Human Skin: One Sequenced Cell at a Time
The article concludes that creating a detailed map of normal human skin at the single-cell level is important.
research Multimodal Molecular Analysis Reveals Divergent Trajectories of Wound Regeneration Versus Fibrosis
Verteporfin treatment in mice led to complete skin healing without scarring.
research Committing to a Hairy Fate: Epigenetic Regulation of Hair Follicle Stem Cells
Epigenetic changes are crucial for hair follicle stem cells to function properly.
research A Transient Dermal Niche and Dual Epidermal Programs Underlie Sweat Gland Development
Sweat gland development involves two unique skin cell programs and a temporary skin environment.
research Desmoglein 4 Is Regulated by Transcription Factors Implicated in Hair Shaft Differentiation
Desmoglein 4 is controlled by specific proteins that affect hair growth.
research The Human Type I Keratin Gene Family: Characterization of New Hair Follicle Specific Members and Evaluation of the Chromosome 17q21.2 Gene Domain
The study identified and characterized new keratin genes linked to hair follicles and epithelial tissues.
research News in Brief
Researchers found potential new targets for treating melanoma and nonmelanoma skin cancers, and identified a possible cause and treatment for male pattern baldness and eczema.
research Recent Updates of the CRISPR/Cas9 Genome Editing System: Novel Approaches to Regulate Its Spatiotemporal Control by Genetic and Physicochemical Strategies
CRISPR/Cas9 has improved precision and control but still faces clinical challenges.
research Resident Memory T Cells in Autoimmune Skin Diseases
Certain immune cells contribute to skin autoimmune diseases, and some treatments can reverse hair loss in these conditions.
research Foxp1 Regulates the Proliferation of Hair Follicle Stem Cells in Response to Oxidative Stress During Hair Cycling
Foxp1 helps control hair stem cell growth and response to stress during hair growth cycles.
research Effects of Boswellia on Hair Cycle-Related Genes in Mice with DNCB-Induced Dermatitis
Boswellia may improve skin inflammation symptoms and positively influence hair growth in mice.
research Alopecia in Harlequin Mutant Mice Is Associated with Reduced AIF Protein Levels and Expression of Retroviral Elements
Harlequin mutant mice have hair loss due to low AIF protein levels and retroviral element activity.
research Establishment of Dermal Sheath Cell Line from Cashmere Goat and Characterizing Cytokeratin 13 as Its Novel Biomarker
Scientists created a new cell line from Cashmere goat hair and found that cytokeratin 13 is a unique marker for certain skin cells.
research The Role of AUTS2 in Neurodevelopment and Human Evolution
The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.