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Activating Nrf2 protects human hair follicles from oxidative stress and helps prevent hair growth inhibition.

The extracellular matrix is crucial for controlling skin stem cell behavior and health.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.

Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.

Skin tumor regression is helped by retinoic acid signaling blocking Wnt signaling.

Noncoding dsRNA boosts hair growth by activating TLR3 and increasing retinoic acid.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.

Injecting a special gel with human protein particles can help hair grow.

Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.

Disrupting Acvr1b in mice causes severe hair loss and thicker skin.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

Hoxc genes control hair growth through Wnt signaling.

Eupafolin nanoparticles help protect skin cells from damage caused by air pollution.

Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

Understanding how melanocyte stem cells work could lead to new treatments for hair graying and skin pigmentation disorders.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Changing the amount of PLC5 in Arabidopsis affects root growth and drought resistance, with less PLC5 slowing root growth and more PLC5 improving drought tolerance but hindering root hair growth.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.

The skin's basement membrane has specialized structures and molecules for different tissue interactions, important for hair growth and attachment.

Minoxidil improves blood flow and vessel flexibility, potentially helping with vascular stiffness.

Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.

Ziziphus jujuba Mills may have health benefits, but more research is needed to confirm its safety and effectiveness.

Polyamines are important for hair growth, but more research is needed to understand their functions and treatment potential.

Immune cells help regulate hair growth, and better understanding this can improve hair loss treatments.