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    Did you mean Transcription Factors?
    Glossary Transcription Factors

    proteins that regulate gene expression by binding to DNA

    Transcription Factors (TFs) are proteins that help turn specific genes on or off by binding to nearby DNA. They play a crucial role in regulating gene expression, ensuring that genes are activated at the right time and in the right cells, which is essential for processes like development, cell growth, and response to environmental signals.

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    Research 30 of 1000+

    1. 126 cAMP response element-binding protein 1 (CREB) is a β-catenin-regulated transcription factor in squamous cell carcinoma (SCC) cells Journal of Investigative Dermatology · 2018
    2. Trps1 activates a network of secreted Wnt inhibitors and transcription factors crucial to vibrissa follicle morphogenesis Development · 2011 · 59 citations
    3. Desmoglein 4 is regulated by transcription factors implicated in hair shaft differentiation Differentiation · 2009 · 35 citations
    4. Structural and biochemical changes underlying a keratoderma-like phenotype in mice lacking suprabasal AP1 transcription factor function Cell Death and Disease · 2015 · 17 citations
    5. Runx1 transcription factor is involved in the regulation of KAP5 gene expression in human hair follicles Journal of dermatological science · 2006 · 6 citations
    6. Skin expression of mammalian target of rapamycin and forkhead box transcription factor O1, and serum insulin‐like growth factor‐1 in patients with acne vulgaris and their relationship with diet British Journal of Dermatology · 2016 · 93 citations
    7. The dark and the bright sides of the transcription factor Nrf2 in skin protection and disease (Nrf2 and epidermal barrier function) Free Radical Biology and Medicine · 2015
    8. 440 Topical application of anti-cancer drug Bortezomib stimulates proliferation of follicular cells and induces expression of hair keratins via GATA-3 transcription factor 2016
    9. Krtap16, Characterization of a New Hair Keratin-associated Protein (KAP) Gene Complex on Mouse Chromosome 16 and Evidence for Regulation by Hoxc13 Journal of Biological Chemistry · 2004 · 47 citations
    10. The keratin proteins and genes of wool and hair. Adelaide Research & Scholarship (AR&S) (University of Adelaide) · 1996 · 15 citations
    11. p53 Is a Direct Transcriptional Repressor of Keratin 17: Lessons from a Rat Model of Radiation Dermatitis Journal of Investigative Dermatology · 2015 · 19 citations
    12. Bone morphogenetic protein (BMP) signaling controls hair pigmentation by means of cross-talk with the melanocortin receptor-1 pathway Proceedings of the National Academy of Sciences · 2004 · 70 citations
    13. Human Hairless Protein Roles in Skin/Hair and Emerging Connections to Brain and Other Cancers Journal of Cellular Biochemistry · 2017 · 15 citations
    14. Factors regulating quiescent stem cells: insights from the intestine and other self-renewing tissues The Journal of Physiology · 2015 · 8 citations
    15. Dermal white adipose tissue development and metabolism: The role of transcription factor Foxn1 ˜The œFASEB journal · 2023
    16. Physical and Functional Interaction between the Vitamin D Receptor and Hairless Corepressor, Two Proteins Required for Hair Cycling Journal of Biological Chemistry · 2003 · 215 citations
    17. Scoparone Induces Expression of Pluripotency Transcription Factors SOX2 and NANOG in Dermal Papilla Cells in Vivo · 2021 · 4 citations
    18. Cortisol Enhances the Expression of mac25/Insulin-Like Growth Factor-Binding Protein-Related Protein-1 in Cultured Osteoblasts**This work was supported by NIDDK Grant DK-45227 and a scholarship (to R.C.P.) from Fundacao Coordenacao de Aperfeicoa mento de Pessoal de Nivel Superior (CAPES), Universidade de Sao Paulo (Sao Paulo, Brazil). Endocrinology · 1999 · 43 citations
    19. Formation of regulator/target gene relationships during evolution Gene · 2000 · 25 citations
    20. Large Scale Gene Expression Profiles of Regenerating Inner Ear Sensory Epithelia PLoS ONE · 2007 · 77 citations
    21. Role of regeneration in tissue repairing and therapies Journal of regenerative medicine & tissue engineering · 2015 · 6 citations
    22. Beauty is skin deep: the fascinating biology of the epidermis and its appendages. PubMed · 2000 · 65 citations
    23. Basonuclin is associated with the ribosomal RNA genes on human keratinocyte mitotic chromosomes Journal of Cell Science · 1999 · 36 citations
    24. Identification and dissection of an enhancer controlling epithelial gene expression in skin Proceedings of the National Academy of Sciences · 2001 · 29 citations
    25. Finasteride Enhances Stem Cell Signals of Human Dermal Papilla Cells in Vivo · 2019 · 10 citations
    26. Langerin+ Dendritic Cells in Cutaneous Fibrosis: The TGF-β1 Signaling Axis Clinical Cosmetic and Investigational Dermatology · 2025
    27. The epidermis: rising to the surface Current opinion in genetics & development · 1994 · 238 citations
    28. Apoptosis May Explain the Pharmacological Mode of Action and Adverse Effects of Isotretinoin, Including Teratogenicity Acta dermato-venereologica · 2017 · 66 citations
    29. More than One Way to Skin a Wound Cell Stem Cell · 2018 · 2 citations
    30. Intermediate filaments: regulation of gene expression and assembly European journal of biochemistry · 1993 · 50 citations