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    Did you mean Transcription Factors?
    Glossary Transcription Factors

    proteins that regulate gene expression by binding to DNA

    Transcription Factors (TFs) are proteins that help turn specific genes on or off by binding to nearby DNA. They play a crucial role in regulating gene expression, ensuring that genes are activated at the right time and in the right cells, which is essential for processes like development, cell growth, and response to environmental signals.

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    Research 30 of 1000+

    1. All Roads Go to the Nucleus: Integration of Signaling/Transcription Factor-Mediated and Epigenetic Regulatory Mechanisms in the Control of Skin Development and Regeneration Stem cell biology and regenerative medicine · 2018
    2. Transcriptional and epigenetic mechanisms governing epidermal stem cell regulation Frontiers in Cell and Developmental Biology · 2026
    3. Transcriptional Control of Epidermal Stem Cells Advances in Experimental Medicine and Biology · 2013 · 4 citations
    4. The Developmental & Molecular Requirements for Ensuring that Human Pluripotent Stem Cell-Derived Hair Follicle Bulge Stem Cells Have Acquired Competence for Hair Follicle Generation Following Transplantation Cell transplantation · 2021 · 4 citations
    5. P63 expression pattern during rat epidermis morphogenesis and the role of p63 as a marker for epidermal stem cells Journal of Cutaneous Pathology · 2006 · 16 citations
    6. p63 regulates <i>Satb1</i> to control tissue-specific chromatin remodeling during development of the epidermis The Journal of Cell Biology · 2011 · 166 citations
    7. Genome-wide p63-Target Gene Analyses Reveal TAp63/NRF2-Dependent Oxidative Stress Responses Cancer Research Communications · 2024 · 7 citations
    8. p63: a crucial player in epithelial stemness regulation Oncogene · 2023 · 54 citations
    9. Vitamin D receptor cross-talk with p63 signaling promotes epidermal cell fate 2023 · 1 citations
    10. 1435 Dynamic morphogen-p63 chromatin interactions that guide epigenetic changes and p63 activity in surface ectoderm commitment Journal of Investigative Dermatology · 2018
    11.  Np63 Regulates Stem Cell Dynamics in the Mammalian Olfactory Epithelium Journal of Neuroscience · 2011 · 93 citations
    12. Requirement of zinc transporter ZIP10 for epidermal development: Implication of the ZIP10–p63 axis in epithelial homeostasis Proceedings of the National Academy of Sciences · 2017 · 59 citations
    13. Formation of the cornified envelope Experimental dermatology · 2005 · 3 citations
    14. Olfactory epithelium regeneration and homeostasis: cellular and molecular mechanisms and novel methodological advances Cell Regeneration · 2026
    15. Regulation of VDR by ΔNp63α is associated with inhibition of cell invasion Journal of Cell Science · 2009 · 34 citations
    16. Role of vitamin D and calcium signaling in epidermal wound healing Journal of endocrinological investigation · 2022 · 15 citations
    17. The Progress of Epidermal Stem Cell Research 2010
    18. The Role of ATP-dependent Chromatin Remodeling in the Control of Epidermal Differentiation and Skin Stem Cell Activity Stem cell biology and regenerative medicine · 2018
    19. The Role of the Vitamin D Receptor in the Epidermal Stem Cell Response to Wounding Receptors · 2024
    20. Expression Patterns of Gli-1, Pleckstrin Homology-Like Domain, Family A, Member 1, Transforming Growth Factor-β1/β2, and p63 in Sebaceous and Follicular Tumors Annals of Dermatology · 2014 · 8 citations
    21. AP-2α/AP-2β transcription factors are key regulators of epidermal homeostasis bioRxiv (Cold Spring Harbor Laboratory) · 2023
    22. AP-2α/AP-2β transcription factors are key regulators of epidermal homeostasis 2024
    23. Prediction of cell states and key transcription factors of the human cornea through integrated single-cell omics analyses PNAS Nexus · 2025
    24. Diverse mechanisms for endogenous regeneration and repair in mammalian organs Nature · 2018 · 172 citations
    25. Epidermal homeostasis: a balancing act of stem cells in the skin Nature Reviews Molecular Cell Biology · 2009 · 1039 citations
    26. The Paradox of p53: What, How, and Why? Cold Spring Harbor Perspectives in Medicine · 2016 · 64 citations
    27. Post-transcriptional Regulation of Keratinocyte Progenitor Cell Expansion, Differentiation and Hair Follicle Regression by miR-22 PLOS Genetics · 2015 · 52 citations
    28. p53 Is a Direct Transcriptional Repressor of Keratin 17: Lessons from a Rat Model of Radiation Dermatitis Journal of Investigative Dermatology · 2015 · 19 citations
    29. Tp63-expressing adult epithelial stem cells cross lineages boundaries revealing latent hairy skin competence Nature Communications · 2020 · 8 citations
    30. SPT6 maintains epidermal homeostasis by inhibiting an NF-κB-positive feedback loop to prevent excessive inflammation Cellular and Molecular Immunology · 2026