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    Glossary Transcription Factors

    proteins that regulate gene expression by binding to DNA

    Transcription Factors (TFs) are proteins that help turn specific genes on or off by binding to nearby DNA. They play a crucial role in regulating gene expression, ensuring that genes are activated at the right time and in the right cells, which is essential for processes like development, cell growth, and response to environmental signals.

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    1. Forkhead/winged-helix transcription factor whn regulates hair keratin gene expression: Molecular analysis of theNude skin phenotype Developmental Dynamics · 2000 · 75 citations
    2. The BLMP-1 transcription factor promotes oscillatory gene expression to achieve timely molting bioRxiv (Cold Spring Harbor Laboratory) · 2021 · 4 citations
    3. Runx1 transcription factor is involved in the regulation of KAP5 gene expression in human hair follicles Journal of dermatological science · 2006 · 6 citations
    4. The Suppression Effects of Fat Mass and Obesity Associated Gene on the Hair Follicle-Derived Neural Crest Stem Cells Differentiating into Melanocyte by N6-Methyladenosine Modifying Microphthalmia-Associated Transcription Factor International Journal of Stem Cells · 2023 · 4 citations
    5. 328 The transcription factor CEBPB is a novel hub gene and multi-functional disease driver in Psoriatic skin inflammation Journal of Investigative Dermatology · 2022
    6. Structural and biochemical changes underlying a keratoderma-like phenotype in mice lacking suprabasal AP1 transcription factor function Cell Death and Disease · 2015 · 17 citations
    7. The Tissue-dependent Keratin 19 Gene Transcription Is Regulated by GKLF/KLF4 and Sp1 Journal of Biological Chemistry · 2000 · 119 citations
    8. Mutations in SREBF1, Encoding Sterol Regulatory Element Binding Transcription Factor 1, Cause Autosomal-Dominant IFAP Syndrome American journal of human genetics · 2020 · 34 citations
    9. NAC transcription factor RD26 is a regulator of root hair morphogenic plasticity bioRxiv (Cold Spring Harbor Laboratory) · 2021 · 1 citations
    10. Identification and characterization of an antisense RNA transcript (gfg) from the human basic fibroblast growth factor gene. Molecular Endocrinology · 1994 · 24 citations
    11. Large Scale Gene Expression Profiles of Regenerating Inner Ear Sensory Epithelia PLoS ONE · 2007 · 77 citations
    12. Formation of regulator/target gene relationships during evolution Gene · 2000 · 25 citations
    13. Basonuclin is associated with the ribosomal RNA genes on human keratinocyte mitotic chromosomes Journal of Cell Science · 1999 · 36 citations
    14. The promoter of an androgen dependent gene in the hamster flank organ Journal of Dermatological Science · 1997 · 6 citations
    15. DNA dioxygenases Tet2/3 regulate gene promoter accessibility and chromatin topology in lineage-specific loci to control epithelial differentiation Science advances · 2023 · 3 citations
    16. Deciphering gene regulatory programs in mouse embryonic skin through single-cell multiomics analysis Genome biology · 2025
    17. Understanding the Molecular Landscape of Alopecia Areata: Key Genes, Regulatory Networks, and Therapeutic Targets Health Science Reports · 2026
    18. Wnt target gene Ascl4 is dispensable for skin appendage development bioRxiv (Cold Spring Harbor Laboratory) · 2024
    19. Regulation of Involucrin Gene Expression Journal of Investigative Dermatology · 2004 · 138 citations
    20. Post-transcriptional Regulation of Keratinocyte Progenitor Cell Expansion, Differentiation and Hair Follicle Regression by miR-22 PLOS Genetics · 2015 · 52 citations
    21. Krtap16, Characterization of a New Hair Keratin-associated Protein (KAP) Gene Complex on Mouse Chromosome 16 and Evidence for Regulation by Hoxc13 Journal of Biological Chemistry · 2004 · 47 citations
    22. Identification and dissection of an enhancer controlling epithelial gene expression in skin Proceedings of the National Academy of Sciences · 2001 · 29 citations
    23. The keratin proteins and genes of wool and hair. Adelaide Research & Scholarship (AR&S) (University of Adelaide) · 1996 · 15 citations
    24. A Kaleidoscope of Keratin Gene Expression and the Mosaic of Its Regulatory Mechanisms International journal of molecular sciences · 2023 · 3 citations
    25. A novel missense mutation (C622G) in the zinc‐finger domain of the human hairless gene associated with congenital atrichia with papular lesions Experimental Dermatology · 2000 · 47 citations
    26. Genetically separable determinants of hair keratin gene expression Developmental Dynamics · 2000 · 27 citations
    27. p53 Is a Direct Transcriptional Repressor of Keratin 17: Lessons from a Rat Model of Radiation Dermatitis Journal of Investigative Dermatology · 2015 · 19 citations
    28. A preliminary study of differentially expressed genes in expanded skin and normal skin: implications for adult skin regeneration Archives of Dermatological Research · 2011 · 16 citations
    29. Multiomics global landscape of stemness-related gene clusters in adipose-derived mesenchymal stem cells Stem Cell Research & Therapy · 2020 · 13 citations
    30. Thyroid hormones and androgens differentially regulate gene expression in testes and ovaries of sexually mature Silurana tropicalis General and comparative endocrinology · 2018 · 13 citations