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    Did you mean Transcription Factors?
    Glossary Transcription Factors

    proteins that regulate gene expression by binding to DNA

    Transcription Factors (TFs) are proteins that help turn specific genes on or off by binding to nearby DNA. They play a crucial role in regulating gene expression, ensuring that genes are activated at the right time and in the right cells, which is essential for processes like development, cell growth, and response to environmental signals.

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    Research 30 of 1000+

    1. Mutations in SREBF1, Encoding Sterol Regulatory Element Binding Transcription Factor 1, Cause Autosomal-Dominant IFAP Syndrome American journal of human genetics · 2020 · 34 citations
    2. Lnc056 Enhances Hair Follicle Stem Cells Proliferation by Binding Transcription Factor HNRNPUL1 to Up-Regulate TRIP6 Expression. PubMed · 2025
    3. 126 cAMP response element-binding protein 1 (CREB) is a β-catenin-regulated transcription factor in squamous cell carcinoma (SCC) cells Journal of Investigative Dermatology · 2018
    4. Forkhead/winged-helix transcription factor whn regulates hair keratin gene expression: Molecular analysis of theNude skin phenotype Developmental Dynamics · 2000 · 75 citations
    5. GLI2 Is Expressed in Normal Human Epidermis and BCC and Induces GLI1 Expression by Binding to its Promoter Journal of Investigative Dermatology · 2004 · 171 citations
    6. LncRNA018392 promotes proliferation of Liaoning cashmere goat skin fibroblasts through up-regulation of CSF1R by binding to SPI1 Research Square (Research Square) · 2023
    7. Cortisol Enhances the Expression of mac25/Insulin-Like Growth Factor-Binding Protein-Related Protein-1 in Cultured Osteoblasts**This work was supported by NIDDK Grant DK-45227 and a scholarship (to R.C.P.) from Fundacao Coordenacao de Aperfeicoa mento de Pessoal de Nivel Superior (CAPES), Universidade de Sao Paulo (Sao Paulo, Brazil). Endocrinology · 1999 · 43 citations
    8. Identification and dissection of an enhancer controlling epithelial gene expression in skin Proceedings of the National Academy of Sciences · 2001 · 29 citations
    9. Hair of the Dog: Identification of a Cis-Regulatory Module Predicted to Influence Canine Coat Composition Genes · 2019 · 14 citations
    10. Thyroid hormones and androgens differentially regulate gene expression in testes and ovaries of sexually mature Silurana tropicalis General and comparative endocrinology · 2018 · 13 citations
    11. Deletion of an enhancer in FGF5 is associated with ectopic expression in goat hair follicles and the cashmere growth phenotype Research Square (Research Square) · 2020
    12. Integrated single-cell chromatin and transcriptomic analyses of human scalp reveal etiological insights into genetic risk for hair and skin disease bioRxiv (Cold Spring Harbor Laboratory) · 2022
    13. 708 Promotion of hair growth in alopecia areata by topical treatment of HDAC inhibitors 2019
    14. Cutaneous Retinoic Acid Levels Determine Hair Follicle Development and Downgrowth 2012 · 31 citations
    15. Allosteric interactions prime androgen receptor dimerization and activation bioRxiv (Cold Spring Harbor Laboratory) · 2022 · 1 citations
    16. Molecular genetics of androgen insensitivity Adolescent and pediatric gynecology · 1995
    17. Genetically separable determinants of hair keratin gene expression Developmental Dynamics · 2000 · 27 citations
    18. Human Hairless Protein Roles in Skin/Hair and Emerging Connections to Brain and Other Cancers Journal of Cellular Biochemistry · 2017 · 15 citations
    19. Langerin+ Dendritic Cells in Cutaneous Fibrosis: The TGF-β1 Signaling Axis Clinical Cosmetic and Investigational Dermatology · 2025
    20. Distinct tooth regeneration systems deploy a conserved battery of genes bioRxiv (Cold Spring Harbor Laboratory) · 2020
    21. Melanogenesis‐promoting effect of <i>Cirsium japonicum</i> flower extract in vitro and ex vivo International Journal of Cosmetic Science · 2021 · 4 citations
    22. Case Series: Gene Expression Analysis in Canine Vogt-Koyanagi-Harada/Uveodermatologic Syndrome and Vitiligo Reveals Conserved Immunopathogenesis Pathways Between Dog and Human Autoimmune Pigmentary Disorders Frontiers in Immunology · 2020 · 20 citations
    23. Physical and Functional Interaction between the Vitamin D Receptor and Hairless Corepressor, Two Proteins Required for Hair Cycling Journal of Biological Chemistry · 2003 · 215 citations
    24. Tribuloside acts on the PDE/cAMP/PKA pathway to enhance melanogenesis, melanocyte dendricity and melanosome transport Journal of ethnopharmacology · 2023
    25. Nerve growth factor regulates the proliferation of cashmere goat outer root sheath cells through the activation of cAMP-binding protein Small ruminant research · 2019 · 1 citations
    26. AabHLH112, a bHLH transcription factor, positively regulates sesquiterpenes biosynthesis in Artemisia annua Frontiers in Plant Science · 2022 · 19 citations
    27. 440 Topical application of anti-cancer drug Bortezomib stimulates proliferation of follicular cells and induces expression of hair keratins via GATA-3 transcription factor 2016
    28. Role of Csdc2 in Regulating Secondary Hair Follicle Growth in Cashmere Goats International Journal of Molecular Sciences · 2024 · 2 citations
    29. HOXC13 Is Involved in the Regulation of Human Hair Keratin Gene Expression Journal of Biological Chemistry · 2002 · 132 citations
    30. Inhibition of CCAAT/Enhancer Binding Protein Family DNA Binding in Mouse Epidermis Prevents and Regresses Papillomas Cancer Research · 2007 · 28 citations