31 citations,
January 2017 in “Advances in Experimental Medicine and Biology” Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.
202 citations,
August 2007 in “Biomaterials” Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.
179 citations,
April 2012 in “Nature Communications” Regenerated fully functional hair follicles using stem cells, with potential for hair regrowth therapy.
75 citations,
February 2016 in “The Journal of Sexual Medicine” Androgens play a role in female sexual function, and testosterone therapy can help women with low sexual desire, but more research is needed on treatments and long-term safety.
1 citations,
October 2022 in “International journal of endocrinology” Dihydrotestosterone changes some hormone-related gene expressions in rat pituitary glands but doesn't affect the estrous cycle.
8 citations,
January 2009 in “Journal of pediatric endocrinology & metabolism/Journal of pediatric endocrinology and metabolism” A specific thyroid hormone resistance mutation may be linked to different types of hair loss.
6 citations,
January 2010 in “Neoplasma” Certain gene patterns in breast cancer are linked to how active hormone receptors are and could affect patient survival.
18 citations,
May 2014 in “Menopause” A 5 mg dose of transdermal testosterone cream effectively restores testosterone levels in postmenopausal women.
January 2017 in “Springer eBooks” Scientists made working hair follicles using stem cells, helping future hair loss treatments.
25 citations,
January 2022 in “Endocrine journal” Long COVID patients may have hormonal imbalances linked to their symptoms.
January 2008 in “Springer eBooks” Thyroid disease can cause hair loss and treating thyroid problems might help with hair disorders.
20 citations,
October 2018 in “American Journal of Clinical Dermatology” Some drugs can cause skin and hair color changes, often reversible when the drug is stopped.
17 citations,
August 2019 in “Archives of Cardiovascular Diseases” Low testosterone in men is a risk factor for a specific heart rhythm issue, and testosterone treatment may help prevent it.
29 citations,
August 2017 in “Skin appendage disorders” IGF-1 may affect hair growth and loss, but more research is needed to confirm effective and safe treatments.
February 2023 in “Frontiers in Endocrinology” Too much male hormone in mothers can negatively affect the sexual behavior of both male and female baby mice.
4 citations,
December 2022 in “Frontiers in Endocrinology” Treating non-classic congenital adrenal hyperplasia is complex because the benefits of hormone treatment must be weighed against potential health risks.
21 citations,
February 2021 in “Frontiers in Endocrinology” Hormones affect prostate health and disease, with certain hormone imbalances linked to prostate cancer and benign prostatic hyperplasia.
9 citations,
October 2017 in “Translational pediatrics” Pediatric endocrinologists should provide early fertility counseling and preservation options to young patients at risk of infertility.
19 citations,
August 2014 in “Journal of Ethnopharmacology” The study created a test that found hormonal and toxic effects in plant and fungal extracts using prostate cancer cells.
35 citations,
April 2008 in “Human Molecular Genetics” Skin and hair can help us understand organ regeneration, especially how certain stem cells might be used to form new organs.
19 citations,
April 2014 in “Hormones” Hormones and genetics play key roles in male and female baldness, which can affect mental health and may be linked to other health issues.
89 citations,
November 2017 in “Journal of Cellular Physiology” The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.
66 citations,
May 2012 in “Scientific Reports” Scientists successfully created and transplanted bioengineered hair follicles that function like natural ones, suggesting a new treatment for hair loss.
10 citations,
October 2010 in “International Journal of Andrology” Finasteride doesn't affect oral testosterone undecanoate, and high DHT levels may cause acne, prostate issues, and hair loss.
1 citations,
November 2018 in “Elsevier eBooks” The document concludes that transplantology has evolved with improved techniques and materials, making transplants more successful and expanding the types of transplants possible.
October 2017 in “Springer eBooks” A thorough initial check-up is essential before sperm banking to ensure the best chance of preserving good quality sperm.
68 citations,
January 2008 in “Seminars in reproductive medicine” Women with PCOS often feel stigmatized and have mood issues, which can lower their sexual satisfaction, but proper treatment and support can help.
22 citations,
October 2011 in “Bone” Androgens affect bone and fat cell development differently based on the cells' embryonic origin.
11 citations,
August 2009 in “Expert Opinion on Drug Discovery” We need better ways to test and understand SARMs to make safer and more effective treatments.
6 citations,
December 2020 in “Dermatological reviews” COVID-19 may worsen with androgens; anti-androgen drugs could help.