March 2024 in “Middle East Fertility Society Journal/Middle East Fertility Society Journal ” In this study, the researchers used dual-energy X-ray absorptiometry and found that women with polycystic ovary syndrome exhibit a central fat distribution pattern despite not having increased overall fat compared to controls, suggesting this method's potential utility in diagnosing and monitoring PCOS.
1 citations
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October 2024 in “Cureus” This study reported that women with polycystic ovarian syndrome have higher serum irisin levels, which are associated with metabolic and hormonal imbalances, including hyperandrogenism, total cholesterol, and visceral fat.
90 citations
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February 2013 in “The Journal of Clinical Endocrinology and Metabolism” This study found that women with polycystic ovary syndrome have higher global adiposity and increased visceral fat, particularly in the ip and mesenteric depots, compared to women without androgen excess.
July 2026 in “Gazi Medical Journal” This study reported that obese women with polycystic ovary syndrome had higher body fat and insulin resistance, and lower HDL cholesterol compared to non-obese patients and healthy controls.
May 2017 in “Endocrine Abstracts” This study found that men with early-onset androgenetic alopecia who also met criteria for the male PCOS-equivalent may have impaired gonadal steroidogenesis, suggesting increased risk of future gonadal dysfunction.
14 citations
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August 2014 in “Applied Physiology, Nutrition, and Metabolism” This study concluded that an 8-week low-starch/low-dairy diet increased fat oxidation in overweight and obese women with PCOS.
10 citations
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February 2017 in “Hormone Molecular Biology and Clinical Investigation” This randomized clinical trial found that vitamin D supplementation did not significantly alter anthropometric or metabolic parameters in obese, insulin-resistant, and vitamin D-deficient women with polycystic ovary syndrome, whereas metformin effectively reduced body weight, BMI, waist circumference, total body fat, and serum glucose levels.
30 citations
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July 2017 in “Stem cells and cloning” This study found that scalp injection of fat enriched with stem cells may offer a promising alternative for treating early genetic alopecia in both men and women.
4 citations
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March 2021 in “International Journal of Environmental Research and Public Health” This study found that women with polycystic ovary syndrome have higher body mass index, fat mass percentage, and skinfold thickness compared to women without PCOS.
29 citations
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October 2020 in “eLife” This study using Mendelian randomization in UK Biobank data suggests that lifelong increased free testosterone may have mixed effects, including increased bone density and prostate cancer risk, warranting well-powered trials to address uncertainties.
1 citations
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January 2017 in “Journal of rare disease research & treatment” Obesity is common in PCOS patients and early treatment is important for their heart and metabolic health.
1 citations
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June 2001 in “Annals of Internal Medicine” This letter to the editor discusses data from a study on troglitazone for lipodystrophy, noting significant increases in subcutaneous fat without dietary changes.
24 citations
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June 2021 in “Agronomy” This study found that biostimulant application in lettuce cultivation led to significant yield and phytochemical enhancements, with effects varying between green and red cultivars depending on the treatment method used.
5 citations
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August 2020 in “Stem Cell Research & Therapy” This study found that combining adipose-derived mesenchymal stromal cells with meglumine antimoniate reduced lesion size and parasite load in mice with leishmaniasis, suggesting potential for improved treatment.
August 2023 in “Stem Cell Research & Therapy” This study found that cell-free fat extract (CEFFE) enhanced hair growth in mice with androgenetic alopecia by increasing hair follicle density and promoting proliferation while regulating the DHT/AR pathway.
5 citations
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January 2016 in “Genetics and molecular research” In this study, a specific SNP in the A2M gene of Murrah buffaloes was significantly associated with increased fat production and higher fat and protein percentages in milk.
4 citations
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June 2021 in “Applied Sciences” This study found that women with PCOS had higher body fat and worse insulin resistance than non-PCOS women, with body composition influencing metabolic profiles independently of PCOS status.
3 citations
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August 2020 in “Nutrition Journal” This study found that spinach-derived thylakoid supplementation, combined with a calorie-restricted diet, led to more significant improvements in weight loss and insulin sensitivity in obese women with PCOS than calorie restriction alone.
12 citations
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October 2018 in “Aging male/The aging male” This study found that prostate cancer aggressiveness in men with obesity is associated with changes in age, BMI, testosterone, and estradiol levels, and that adipocyte-secreted molecules increase cancer cell aggressiveness in vitro.
2 citations
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April 2023 in “Stem Cell Research & Therapy” This study found that small extracellular vesicles derived from human adipose tissue could promote soft tissue regeneration and increase M2 macrophage polarization, suggesting a promising cell-free approach to tissue repair.
19 citations
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July 2015 in “Journal of inherited metabolic disease” This study observed that while betaine supplementation decreases total homocysteine and increases methionine levels in a mouse model of CBS deficiency, it is not as effective as methionine restriction in reversing associated phenotypes.
1 citations
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December 2006 in “Burns” New therapies for burn wounds show promise in reducing pain, infection risk, and improving healing and physical outcomes.
28 citations
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November 2013 in “The FASEB journal” In this study, a low-methionine diet significantly improved the health and physical traits of cystathionine β-synthase-deficient mice, contrasting with negative effects on mice with partial deficiency.
105 citations
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February 2011 in “The Journal of Clinical Endocrinology & Metabolism” Treating sleep apnea in young obese women with PCOS can improve heart health and insulin sensitivity.
18 citations
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September 2015 in “Clinical Endocrinology” This study found that women with polycystic ovary syndrome have higher serum VEGF-B levels, which are linked to insulin resistance and decrease after metformin treatment.
December 2023 in “Journal of the Endocrine Society” In this study, the researchers found that glucocorticoid receptor activation may influence glucose metabolism, with preventive GR antagonist treatment reducing hyperglycemia and restoring glucose tolerance in a PCOS mouse model.
11 citations
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September 2007 in “Advances in therapy” This study found that the oral supplement INVERSION® Femme significantly reduced weight and hair loss and improved skin and nails in overweight women.
In this study, a very low-calorie ketogenic diet significantly improved metabolic and hormonal profiles in obese men, but did not significantly enhance most semen parameters except for sperm motility.
December 2025 in “IntechOpen eBooks” This source critically examines the limitations of using BMI to assess obesity in women, especially during reproductive, pregnancy, and postmenopausal stages, and discusses more precise alternative methods for evaluating obesity in line with sex-specific healthcare needs.
21 citations
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December 2012 in “Biological Trace Element Research” Higher hair levels of calcium and magnesium are linked to higher body weight, while lower levels are linked to worse metabolic health.