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TNF-a may not be as involved in certain types of hair loss as previously thought.

Antidepressants might help with skin inflammation and improve conditions like psoriasis and eczema.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

Pantethine may boost the immune system's ability to fight sarcoma.

Understanding how baby skin heals without scars could help develop treatments for adults to heal wounds without leaving scars.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Hair loss from Alopecia Areata is caused by both genes and environment, with several treatments available but challenges in cost and relapse remain.

Blocking certain immune signals can reduce skin damage from radiation therapy.

Both vitiligo and alopecia areata involve an immune response triggered by stress and specific genes, with treatments targeting this pathway showing potential.

Tocilizumab treatment was associated with significant hair regrowth in one patient and temporary hair loss followed by regrowth in another.

Skin problems are common in lupus, often appearing first, with various types and treatments, and careful monitoring is important for diagnosis and management.

The hexosamine pathway helps protect skin cells from stress and may improve skin and hair health.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

Tofacitinib citrate is effective for moderate-to-severe chronic plaque psoriasis but has safety concerns at higher doses.

Keratin 17 is modified by RSK1 in response to growth and stress, affecting skin growth and stress response.

Dermoscopy helps diagnose unusual skin lesions like osteonevus of Nanta and can prevent misdiagnosis of serious conditions.

Lymphatic vessels are essential for health and can be targeted to treat various diseases.

Triptolide effectively and safely reduces actinic keratosis lesions in mice.

Cow milk sugars increase fat production and inflammation in skin oil cells.

A boy with Oculodentodigital syndrome had a unique GJA1 gene mutation causing his symptoms.

The BMP/Smads pathway and Id2 gene control hair follicle stem cells, affecting their rest and growth phases.

Scientists created a tiny, 3D model of a hair follicle that grows and acts like a real one.

The model and estimator can predict drug exposure in kidney transplant patients well.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Managing metabolic syndrome needs both lifestyle changes and medical treatments.

The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.

Photobiomodulation therapy using red and near-infrared light can reduce inflammation and aid in healing various conditions.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.