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Human skin can provide stem cells for tissue repair and regeneration, but there are challenges in obtaining and growing these cells safely.

Injection lipolysis effectively reduces small fat deposits and should be done with care and proper patient selection.

Scaffold-based strategies show promise for regenerating hair follicles and teeth but need more research for clinical use.

Finasteride effectively treats male hair loss, improving growth and density.

Engineering the cell microenvironment is key for advancing tissue engineering and regenerative medicine.

Understanding and manipulating epigenetic changes can potentially lead to human organ regeneration therapies, but more research is needed to improve these methods and minimize risks.

Mice can regenerate ear tissue without the p53 protein.

Hair follicles can be used to quickly assess drug effects in cancer treatment.

Collagen makes skin stiff, and preservation methods greatly increase tissue stiffness.

Nail stem cells and Wnt signaling are important for fingertip regeneration but not sufficient for regenerating more complex limb structures.

Melatonin affects skin and hair color and protects skin cells, with potential benefits for hair growth and skin health.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Radiation therapy in breast cancer patients changes gene expression related to DNA damage, fibroblast growth, and hair follicle development, which could help improve treatment for radiation-induced fibrosis.

Keratin proteins are essential for keeping the cells in the human colon healthy and stable.

Estrogen is important for keeping adult mouse nipple skin healthy by controlling certain cell signals.

Jasmonic acid helps plants grow, defend against threats, and survive stressful conditions like drought and salt.

More research is needed to understand how diet affects isotope signatures in Japanese macaque tissues.

Low-Level Laser Therapy can stimulate healing and cell function, potentially leading to wider medical use.

Blood vessels and specific genes help turn cartilage into bone when bones heal.

Turning scar-forming cells into fat cells can reduce scarring.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

K42 and K124 keratins are only found in horse hoof lamellae.

Higher TGF-β signaling may increase skin cancer risk in organ transplant recipients.

Skin organoids from stem cells could better mimic real skin but face challenges.

AIRE protein, defective in APECED patients, is found in skin and hair cells and interacts with cytokeratin 17.

Different proteins are linked to the varying thickness of sheep and goat hair types.

Androgens affect bone and fat cell development differently based on the cells' embryonic origin.

The document concludes that while some organisms can regenerate body parts, mammals generally cannot, and cancer progression is complex, involving mutations rather than a strict stem cell hierarchy.

scINSIGHT accurately identifies cell clusters and gene patterns in complex data.

Three characteristics of plasmacytoid dendritic cells help tell apart lupus-related hair loss from LPP.