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The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Wnt signaling is crucial for pigmented hair regeneration by controlling stem cell activation and differentiation.

Oxidative stress contributes to hair graying and loss as we age.

Hair ages due to genetics and environmental factors, leading to graying and thinning, with treatments available for some conditions.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

The conclusion is that certain genetic factors and blood types may affect COVID-19 severity, but changes in ACE2 and TMPRSS2 genes are not clearly linked to it.

Gray hair can potentially be reversed, leading to new treatments.

The congress highlighted new gene therapy techniques and cell transplantation methods for treating diseases.

The engineered yeast strain BLYAS can quickly and sensitively detect androgenic chemicals.

Allopregnanolone changes gene expression in glioblastoma cells.

New treatments like nanotechnology show promise in improving skin cancer therapy.

Rapamycin reduces skin cell growth and tumor development by affecting cell signaling in mice.

Phosphorylation controls TFEB's location in the cell, affecting cell metabolism and stress response.

DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.

Minoxidil and Finasteride are effective for male baldness; more research is needed for hair aging treatments.

Sex hormones' effects on COVID-19 are unclear and more research is needed to understand their potential as treatment.

The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.

Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.

PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.

Muscles can make their own androgens, which may help muscle growth.

Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.

The Hairless gene is crucial for healthy skin and hair growth.

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.

Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.

Clinicians should use social and prescription data to track trends in performance-enhancing drug use.

The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.