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A genetic mutation caused severe rickets and alopecia in an Indian patient, but high-dose calcium and phosphate treatment improved their condition.

Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.

Lower adrenal hormone levels may cause hair loss in postmenopausal women, certain patterns help diagnose nail cancer, and a gene variant linked to higher skin cancer risk in kidney transplant patients suggests monitoring folate levels.

Environmental factors like diet and vitamin levels, especially Vitamin D, can affect autoimmune diseases differently, with lifestyle changes potentially improving outcomes.

People with hidradenitis suppurativa often have lower vitamin D levels, weaker hip bones, and altered bone metabolism markers.

People with alopecia areata have much lower Vitamin-D levels than healthy individuals.

Vitamin D and estrogen may help protect heart and kidney health, and maintaining sufficient vitamin D levels could be especially beneficial for African Americans, postmenopausal women, and people with chronic kidney disease.

Both topical calcipotriol and narrowband UVB improved alopecia, but combining them didn't enhance the effect on hair loss severity, despite higher vitamin D3 levels.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

Intravenous calcium therapy is a safe and effective treatment for a rare type of rickets.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

Lithocholic acid helps hair growth and regeneration in alopecia by activating vitamin D receptors.

Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.

Vitamin D receptor is crucial for bone health and mineral metabolism.

Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.

Patients with the same genetic mutation for vitamin D-resistant rickets showed different symptoms but all improved with treatment except for hair loss.

Hair ages due to various factors and treatments like minoxidil and finasteride can help, but more research and better public awareness are needed.

Skin biopsies are recommended for confirming alopecia diagnosis due to variability in clinical assessments; the link between vitamin D levels and alopecia is unclear.

DPP4-positive fibroblasts play a major role in producing proteins that lead to skin fibrosis.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Hairless protein is crucial for healthy skin and hair, and its malfunction can cause hair loss.

Removing vitamin D and calcium receptors in mice skin cells slows down skin wound healing.

Four patients with a type of rickets and hair loss had different mutations in their vitamin D receptor gene, causing it to not work properly.

Vitamin D boosts a specific protein in skin cells linked to hair follicles.

The document concludes that PCOS has a strong genetic component, but more research is needed to fully understand the specific genes involved.

Certain gene variations in the Vitamin D receptor may increase the risk of chronic hair loss.

Vitamin D Receptor is crucial for hair follicle shrinkage and cell death, affecting hair growth.

Removing REDD1 in mice increases skin fat by making fat cells larger and more numerous.