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Aleglitazar and its major metabolite are safe enough to proceed to Phase 3 clinical trials.

Early treatment and weight management are important for teenagers with PCOS to reduce symptoms and long-term health risks.

Bioinspired polymers are promising for advanced medical treatments and tissue repair.

Testosterone affects blood pressure control and inflammation in male rats with endotoxic shock, and blocking certain hormones may help treat it.

5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.

New Australian advertising rules improved stem cell marketing practices but further regulation is needed for consumer safety.

A man developed a rare skin condition and drug-induced lupus, highlighting the need for biopsy in diagnosing skin issues caused by sunlight.

Future research should focus on making bioengineered skin that completely restores all skin functions.

Using combined treatments can help manage acne by targeting the bacteria and skin changes that cause it.

Zebrafish with mutations similar to human Cantú Syndrome have heart cells with altered channel properties, making them a good model to study the condition.

The document concludes that sex hormones and related compounds have various effects on health, with both potential benefits and risks.

Women's hair gets thinner and grayer as they age, with treatments available for hair loss and graying.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.

Obesity is linked to various skin problems and may increase the risk of skin cancer.

Hormonal treatments can help with acne, especially in women, by lowering androgen levels or blocking their effects.

Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.

Low doses of mixed chemicals cause permanent reproductive malformations in male rats.

Scarring alopecias are complex hair loss disorders that require early treatment to prevent permanent hair loss.

Excessive hair growth can be assessed by history, exam, and blood tests, and treated with medication like dexamethasone, birth control pills, and spironolactone.

The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.

Injection lipolysis effectively reduces small fat deposits and should be done with care and proper patient selection.

Spiny mice are better at regenerating hair after injury than laboratory mice and could help us understand how to improve human skin repair.

Applying calreticulin can speed up wound healing in diabetics.

Mice lacking fibromodulin have disrupted healing patterns, leading to abnormal skin repair and scarring.

Girls with PCOS during adolescence have a higher risk of developing type 2 diabetes, and early treatment can help manage this risk.

Smartphone-based teledermatology is effective for diagnosing skin diseases in the military with good accuracy.

Lupus can look like hair loss from alopecia areata but needs different treatment.

Fat stem cells from diabetic mice can still help heal wounds.

Certain zinc transporters are essential for healthy skin and managing zinc in the body could help treat skin problems.