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Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

Thyrotropin-Releasing Hormone helps heal wounds in frog and human skin.

A new mutation linked to partial Androgen Insensitivity Syndrome and prostate cancer was found in a patient unhappy with their female gender assignment.

Mutations in the androgen receptor gene cause different levels of androgen insensitivity, making it hard to create simple tests for the condition.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Hypothyroidism is often linked to the hair loss condition telogen effluvium.

Vitamin D receptor knockout mice have significant motor impairments but no cognitive deficits.

Thyroid problems can cause hair loss and change hair texture.

The HR protein's role as a repressor is essential for controlling hair growth.

Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.

DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.

Vitamin D Receptor is crucial for normal skin and hair growth.

Hairless protein can block vitamin D activation in skin cells.

Vitamin D3 may protect rat hair follicles from radiation damage.

Blocking prolactin increases the activity of secondary hair follicles in cashmere goats.

People with hair loss conditions may also have thyroid disorders, but more research is needed to understand the connection.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Antiandrogens can treat female hormonal conditions, but environmental ones may harm reproductive health.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Mutations in the Vitamin D receptor gene can cause hair loss similar to mutations in the Hairless gene.

Male pattern baldness involves hormones and cell signals affecting hair growth.

TCDD speeds up skin barrier formation by increasing certain gene expressions.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

As skin cells mature, vitamin D receptor levels decrease while retinoid X receptor α levels increase.

Mice without active or present vitamin D receptors maintain normal blood sugar control and islet gene expression when calcium levels are normal.

The vitamin D receptor can act without its usual activating molecule, affecting hair growth and skin cancer, but its full range of actions is not well understood.

Most patients with telogen effluvium had low iron and vitamin D levels; iron supplements were commonly prescribed.