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Changes in keratin affect skin health and can lead to skin disorders like blistering diseases and psoriasis.

Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.

A man with multiple autoimmune diseases developed liver injury from azathioprine, but his liver improved after stopping the drug.

Hypothyroidism is often linked to the hair loss condition telogen effluvium.

The Rotterdam Study investigates diseases in older adults and has produced many research findings.

Hair changes can indicate systemic diseases or medication effects.

Women with myotonic dystrophy might get diseases related to male hormones because their body tissues are extra sensitive to these hormones.

The document concludes that parathyroid diseases have a range of clinical features and outcomes, with some conditions being treatable and others having a high risk of mortality.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

The Rotterdam Study aims to understand various diseases in older adults.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

Hair mineral analysis might help diagnose diseases early, but standard methods are needed.

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.

People with Lichen Planopilaris are more likely to have autoimmune diseases, especially Systemic Lupus Erythematosus, and less likely to have diabetes and some other common conditions.

Stem cell therapies show promise for treating various diseases but face challenges in clinical use and require better monitoring techniques.

Hair and nails can help diagnose diseases, with nail issues often linked to skin conditions and hair loss having various causes and treatments.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

Good nutrition and vitamins are important for healthy skin and can prevent diseases.

A thorough history and examination are crucial for diagnosing skin diseases, which affect up to a third of people. This includes details about skin lesions, medication, general health, lifestyle, family, and contacts, as well as examining the rash, hair, nails, and mucous membranes. Changes in hair and nails can also indicate other medical and skin disorders.

Some skin conditions are associated with other serious diseases, and office microscopy may miss many fungal infections.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Growth factors are crucial for hair development and could help treat hair diseases.

Skin changes can help diagnose and manage endocrine disorders like thyroid problems, diabetes, and adrenal gland conditions.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Old neuropharmacological drugs might be effective for treating inflammatory skin diseases.

The Androgen Receptor could be a target for treating diseases like cancer, but more research is needed to confirm the effectiveness of potential treatments.

KRT80 may worsen cancer by increasing growth and spread, but its full effects on treatment and outcomes need more research.

Hormone imbalances from the pituitary, thyroid, and adrenal glands can cause infertility, but treating these disorders can improve fertility.

Histone demethylases play a key role in the development of many diseases and may be targets for treatment.