12 citations
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August 2014 in “Elsevier eBooks” This article discusses thallium absorption, excretion, and its toxic effects on humans and animals, emphasizing the need for monitoring in areas with significant environmental contamination; no new clinical results are reported.
St. John’s wort changes how finasteride works in the body, possibly affecting its effectiveness.
3 citations
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October 1993 in “Endocrinology” In this study, finasteride inhibited progesterone synthesis in mouse-derived MA-10 Leydig tumor cells by blocking cholesterol side-chain cleavage, but human and rat cells showed minimal sensitivity.
4 citations
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July 2018 in “The Journal of Allergy and Clinical Immunology: In Practice” This review discusses both occupational asthma, caused by work, and work-exacerbated asthma, reporting no new clinical results and highlighting their prevalence in industrialized nations.
132 citations
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January 1987 in “Annals of Internal Medicine” Methimazole may cause skin defects in babies if taken during pregnancy.
November 2022 in “The Indian journal of chest diseases & allied sciences” This case report documents a rare instance of hair loss associated with isoniazid initiation in a 32-year-old male undergoing antitubercular treatment.
5 citations
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November 2015 in “Journal of Enzyme Inhibition and Medicinal Chemistry” This study found that aliphatic ester moieties in 16-formyl-17-methoxy dehydroepiandrosterone derivatives increased their potency as 5α-reductase type 2 inhibitors in vitro compared to finasteride.
January 2024 in “Bratislavské lekárske listy/Bratislava medical journal” This study examined the vasorelaxant effects of two similar alkaloids, chloroquine and cinchonine, in a model of smooth muscle contractions induced by phenylephrine. Results are not reported in the abstract.
June 2014 in “Belarusian State Pedagogical University repository (Belarusian State Pedagogical University)” In this study, progesterone showed anticonvulsant effects in mice via a mechanism that is at least partially independent of its metabolism to THP, without significant psychotoxicity.
This study reports that a novel series of compounds can potently and selectively inhibit glycogen synthase kinase-3, which activates glycogen synthase in insulin receptor-expressing cells and primary rat hepatocytes.
100 citations
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May 2003 in “Journal of Neuroscience” This study found that neuroactive steroids like DHEA and pregnenolone influence cocaine-induced appetence in mice through their interaction with the ς1 receptor, suggesting a role in individual vulnerability to addiction.
April 2006 in “Pediatrics in Review” This review covers the diagnosis and management of childhood Graves disease, emphasizing treatment options such as antithyroid medications, radioiodine therapy, and surgical thyroidectomy, and highlights the necessity for lifelong follow-up.
February 2022 in “Cleveland Clinic Journal of Medicine” This case report observed hypertrichosis on the left forearm of an 80-year-old woman, possibly linked to her previous use of the topical steroid betamethasone butyrate propionate for dermatitis.
1 citations
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May 2021 in “Thyroid Research and Practice” This study found that low-dose radioactive iodine therapy for hyperthyroidism and thyroid cancer produced short-term adverse effects like loss of taste, xerostomia, and hair loss, which were self-limiting.
119 citations
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June 2005 in “Journal of Molecular and Cellular Cardiology” This article reviews the therapeutic potential of potassium channel openers for various conditions related to metabolic distress but does not report new clinical results; it emphasizes the need for further research.
68 citations
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April 2012 in “Digestive and Liver Disease” This study found that both Elental and 6-mercaptopurine were effective for maintaining remission in Crohn's disease, without a significant difference between them over 24 months.
March 2021 in “Arrow - TU Dublin (Technological University Dublin)” This study tested a folate-conjugate drug delivery system and found its cytotoxicity depends on whether the treated cells overexpress folate receptors, suggesting potential for targeted chemotherapy.
186 citations
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December 2011 in “Molecules” This study reported that while no synthesized compounds surpassed finasteride in 5α-reductase inhibitory activity, certain 4-azasteroid-2-oximes exhibited notable inhibition.
December 2024 in “PubMed” This study reports a case where cyclosporine effectively treated a 51-year-old woman with idiopathic follicular mucinosis resistant to other therapies, suggesting its potential as an option for refractory cases.
2 citations
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October 2010 in “BMB Reports” In this study, L-threonate was observed to inhibit DHT-induced DKK-1 expression in dermal papilla cells and reverse DHT's inhibitory effects on outer root sheath cell growth, suggesting potential as a treatment for androgen-driven balding.
August 1978 in “Dicp-The annals of pharmacotherapy” Mannitol diuresis allows higher doses of cis-platinum for testicular cancer treatment without increasing kidney damage.
1 citations
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March 2016 in “Neurotoxicity Research” In this study, finasteride pretreatment led to EEG changes in rats that suggest a mild reduction in thioacetamide-induced hepatic encephalopathy.
January 1989 in “Side effects of drugs annual” This chapter reviews studies on the side effects of cytostatics and immunosuppressive drugs, detailing various toxicities such as cardiovascular, pulmonary, and neurotoxicity, but provides no new clinical results.
1 citations
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January 2022 in “Journal of Drug Delivery Science and Technology” This study successfully developed and optimized ethanol-free microemulsion systems for the transdermal delivery of finasteride, showing that the predicted optimal formulations had physicochemical characteristics close to estimated values, without significant damage to treated hair fibers.
3 citations
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May 1963 in “Radiology” This article reports on five cases of thallium poisoning seen at Hospital Dos de Mayo, Lima, Peru, highlighting the clinical symptoms and diagnostic features observed, including a case confirmed through various laboratory tests.
103 citations
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April 2005 in “Experimental dermatology” This study found that PGF2alpha analogues and PGE2 stimulated hair follicle activity in mice, with PGF2alpha analogues also linked to potential side effects like poliosis when used as eye treatments.
1 citations
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October 2025 in “Ophthalmology Science” In this experimental study, researchers found that intravitreal injections of up to 100μg of topotecan in rabbits caused no systemic or ocular toxicity, while 200μg doses resulted in localized retinal changes and decreased electroretinography amplitudes near the injection site.
8 citations
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April 2014 in “Anti-Cancer Drugs” In this study, PTH–CBD displayed dose-dependent effects in reducing hair loss and enhancing hair regrowth in a mouse model of chemotherapy-induced alopecia.
March 2024 in “Intisari Sains Medis” This study highlights that juvenile SLE patients, particularly with lupus nephritis and critical conditions, may have a higher risk of thyroid dysfunction and low FT4, potentially worsening their prognosis.
65 citations
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September 1999 in “The Journal of Dermatology” In this study, complete to excellent hair regrowth was observed in 63.3% of patients with extensive alopecia areata treated with biweekly dexamethasone pulses, although mild side effects were frequent.