Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review discusses the therapeutic potential of costunolide for various diseases, highlighting its bioactivity and mechanisms, but it reports no new experimental results.

This review discusses the complex relationship between stress and various skin conditions, highlighting the role of the skin in the stress response and the brain-skin communication pathways, but reports no new research findings.

In this study, researchers used an evolutionary-rate-based method to identify genetic elements associated with reduced hair in mammals, finding a dichotomy between accelerated coding sequences and noncoding regulatory elements influencing hair growth.

This review discusses progress in targeted therapies for vitiligo, focusing on Janus kinase inhibitors and the potential of mesenchymal stem cells, but reports no new clinical results.

This review discusses the expanded understanding of WNT10B's role in various tissues and diseases over the past decade, emphasizing its genetic correlations and potential therapeutic implications, but reports no new clinical results.

This review discusses the applications and potential of Bioengineered Artificial Skin Substitutes in cosmetics and pharmacology research, with no new clinical findings reported.

This study found that PGRP-S expression in mouse epidermis is specific to certain hair follicle epithelia, depending on the skin region, and can be transiently induced in flank skin hair follicle epithelium after exposure to Staphylococcus aureus, suggesting a role in environmental surveillance.

This review summarizes recent findings about the multi-site differentiation of tissue regulatory T cells, emphasizing the pivotal role of epigenetic remodeling, but it reports no new clinical results.

This study found that intron 3 VNTR polymorphism in the IL-4 gene may be associated with an increased risk of alopecia areata in the Turkish population.

This article reviews current and emerging treatments for alopecia areata, emphasizing the need for biomarker-driven patient stratification to optimize therapeutic strategies and reduce potential side effects; it reports no new clinical findings.

This study found that patients with alopecia areata in Dubai experience significant disease and economic burdens, especially when comorbid with psychological conditions, despite frequent dermatologist consultations and topical steroid prescriptions.

Asthma may increase the risk of alopecia areata.

This review by two dermatologists suggests that hair on the human scalp may protect against skin cancer not just physically, but by enabling IL-17 immune surveillance, with hair loss potentially leading to increased tumor growth due to reduced immunosurveillance.

This review reports that thermal spring waters, enriched with a diverse hydrobiome, hold promising potential for use in dermocosmetics, as their bioactive compounds could enhance skin protection, repair, and appearance, benefiting conditions like atopic dermatitis and rosacea.

This review discusses potential biomarkers for alopecia and their significance, and while it highlights areas for future research, it reports no new clinical results.

This review discusses the roles and interactions of intestinal intraepithelial lymphocytes in maintaining mucosal barrier integrity and highlights how their dysregulated responses may contribute to intestinal pathologies.

This review discusses the similar immune pathways and genetic risk factors of vitiligo and alopecia areata but reports no new clinical findings, emphasizing the potential for shared treatment research.

This review examines the role of Sonic Hedgehog signaling in the maintenance and repair of skin and lung barriers, and its influence on inflammation and atopic diseases; it presents no new clinical findings.

This review discusses the role of TGM3 in skin and hair follicle biology, human tumor pathology, and genetic abnormalities, and reports no novel results; the authors highlight its potential as a cancer diagnostic biomarker.

This study suggests that antihistamines show promise as adjunct treatments for alopecia areata, but the role of dupilumab needs further investigation due to mixed results regarding hair regrowth and adverse effects.

In this study, Japanese patients with alopecia areata were found to have higher BMI and retinol intake, with retinol intake predicting severity of hair loss.

This review highlights significant advancements over the past 20 years in understanding the unique dermatological characteristics and needs of skin of color populations, though continued efforts are needed to address remaining disparities.

In this review, researchers reported that pyroptosis, a type of inflammatory cell death linked to inflammasome activity, is a key factor in the pathogenesis of alopecia areata and may present new therapeutic opportunities, though most treatments are still in early research stages.

The study investigated immune cell patterns around the hair follicle infundibulum in androgenetic alopecia, revealing significant differences in immune signatures between patients with AGA and control donors, specifically noting an enrichment of CD4 cells in the patient group.

This study demonstrates that T-cell responses in extensive alopecia areata scalp may be aberrantly regulated, with reduced cytokine production but activated phenotype, providing insight into the disease's immune mechanisms.

This review discusses the role of the skin microbiome in maintaining health and modulating atopic dermatitis, emphasizing the need for novel therapeutic strategies, but reports no new clinical results.

This review explores the emerging roles of NK cells in various diseases, including allergies and skin conditions, and reports no new clinical results while indicating NK cell involvement in immune processes.

This paper explores the complex immune processes and cellular diversity that enable the skin to heal and resist invasion, and highlights its potential as a model for studying regeneration.

This study found that chronic low-grade inflammation exists independently of excess weight or obesity in women with PCOS, with notable increases in specific cytokines such as IL-9, MCP-3, and MIP-1α.

This review compiles current evidence on the molecular mechanisms, etiologies, and targeted immunotherapies for alopecia areata and reports no new experimental results, emphasizing the need for further research to manage the disease.