13 citations
,
June 2020 in “BMC genomics” A specific microRNA, chi-miR-30b-5p, slows down the growth of hair-related cells by affecting the CaMKIIδ gene in cashmere goats.
13 citations
,
January 2020 in “Scientific Reports” The African spiny mouse heals skin without scarring due to different protein activity compared to the common house mouse, which heals with scarring.
9 citations
,
October 2012 in “Frontiers of Hormone Research” Antiandrogens are the main treatment for hirsutism, with individualized care and safe, affordable options needed.
7 citations
,
November 2014 in “Histochemistry and Cell Biology” The we/we wal/wal mice have defects in hair growth and skin layer formation, causing hair loss, useful for understanding alopecia.
5 citations
,
November 1999 in “Medical Hypotheses” Minoxidil, a common hair loss treatment, might work by counteracting a hormone that reduces hair growth and promotes hair loss.
December 2023 in “Linköping University medical dissertations” Keratinocytes and adipose-derived stem cells can effectively heal difficult skin wounds.
May 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” Li2CO3 improved skin disease in a mouse model of Focal Dermal Hypoplasia without toxicity.
January 2017 in “Brazilian Journal of Pharmaceutical Sciences” Arteannuin might work against cancer and Alzheimer's by targeting neprilysin.
September 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Freezing gamma-irradiated amniotic fluid may help hair growth and speed up the growth phase.
January 2017 Dermal stem cells help regenerate hair follicles and heal skin wounds.
298 citations
,
January 2014 in “BioMed Research International” Stem cell-derived conditioned medium shows promise for treating various medical conditions but requires standardized production and further validation.
233 citations
,
February 2018 in “Polymers” Chitin and chitosan are useful in cosmetics for oral care, haircare, and skincare, including UV protection and strength improvement.
144 citations
,
November 2020 in “Frontiers in immunology” Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.
92 citations
,
August 2017 in “Proceedings of the National Academy of Sciences of the United States of America” Newborn mouse skin cells can grow hair and this process can be recreated in adult cells to potentially help with hair loss.
89 citations
,
January 2009 in “Advances in Clinical Chemistry” Fetal skin heals without scarring due to unique cells and processes not present in adult skin healing.
76 citations
,
June 2015 in “Journal of biomedical science” Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.
71 citations
,
January 2015 in “Journal of molecular cell biology/Journal of Molecular Cell Biology” mTOR signaling helps activate hair stem cells by balancing out the suppression caused by BMP during hair growth.
67 citations
,
January 2020 in “Cellular & Molecular Immunology/Cellular & molecular immunology” Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.
67 citations
,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” The document concludes that alopecia areata is an autoimmune disease without a definitive cure, but treatments like corticosteroids are commonly used.
66 citations
,
May 2021 in “Science Advances” Different scaffold patterns improve wound healing and immune response in mouse skin, with aligned patterns being particularly effective.
64 citations
,
April 2005 in “Journal of Investigative Dermatology” Brain-Derived Neurotrophic Factor (BDNF) slows down hair growth and promotes hair follicle regression.
61 citations
,
June 2018 in “Proceedings of the National Academy of Sciences of the United States of America” Light can turn on hair growth cells through a nerve path starting in the eyes.
60 citations
,
May 2015 in “Archives of dermatological research” PPAR agonists show promise for skin conditions but need more research before being a main treatment.
54 citations
,
April 2019 in “Journal of cellular physiology” miR-218-5p helps skin and hair growth by targeting SFRP2 and activating a specific signaling pathway.
51 citations
,
June 2014 in “Drug Discovery Today” Small molecule drugs show promise for advancing regenerative medicine but still face development challenges.
35 citations
,
April 2008 in “Human Molecular Genetics” Skin and hair can help us understand organ regeneration, especially how certain stem cells might be used to form new organs.
31 citations
,
July 2017 in “Clinical Science” MicroRNAs are important for skin health and could be targets for new skin disorder treatments.
28 citations
,
August 2007 in “Development” TAF4 is important for skin cell growth and helps prevent skin cancer in mice.
27 citations
,
July 2017 in “European Journal of Dermatology” Certain microRNAs are linked to various skin diseases and could be used to diagnose and treat these conditions.
24 citations
,
October 2017 in “Biomolecules” Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.