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Exposure to certain sex hormones can increase health risks, while some hormone therapies may offer benefits for specific conditions.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

PCOS is linked to a higher risk of endometrial cancer but not ovarian or breast cancer, and more research is needed on its role in cancer development and treatment effects.

Taking low-dose spironolactone and metformin together works better for PCOS symptoms than either drug alone.

Older men with low levels of a testosterone byproduct had a higher chance of developing an irregular heartbeat.

Three siblings with a rare genetic condition had abnormal sexual development and chose different gender identities, needing surgery and therapy.

The document concludes that hormone therapy is essential for treating gender dysphoria, with specific drugs and monitoring protocols recommended for safety and effectiveness.

Women with Polycystic Ovary Syndrome (PCOS) have lower levels of a substance called DIAPH1 in their blood, which is linked to changes in sugar metabolism and insulin resistance.

Diagnosing sex development disorders requires combining medical history, physical exams, imaging, lab tests, and genetic data.

Miliacin may help prevent hair loss and improve hair growth in mice with a condition similar to human baldness.

Some medications might contribute to male infertility, with finasteride showing a high number of reports.

Hormone treatment for transsexual individuals is effective but carries risks like thromboembolic events and mood changes, with most side effects being minor and reversible.

A certain mutation in the fetal alpha 5-reductase gene is linked to a higher risk of late miscarriage.

Using anabolic-androgenic steroids can harm men's reproductive health and increase the risk of heart problems and death.

A woman had a rare liver tumor causing male-like physical changes, highlighting the need for thorough checks when such symptoms appear.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Gender-affirming hormone therapy improves physical performance in trans men to the level of cisgender men, while in trans women, it increases fat mass and decreases muscle mass, with no advantage in physical performance after 2 years.

Hormonal imbalances can cause hair loss, and understanding them can help develop better treatments.

Sex hormones' effects on COVID-19 are unclear and more research is needed to understand their potential as treatment.

Exosomes from hair papilla cells and the Chinese medicine Liao Tuo Fang can potentially promote hair growth and could be used to develop hair growth drugs.

Testosterone makes the connections in the uterus lining simpler and lowers certain protein levels, which might lead to infertility.

Injecting 2 ml of TEEV every 4 weeks is better because it has the same benefits but fewer side effects.

Testosterone treatment in trans men increases body and facial hair and may lead to hair loss over time, but severe skin issues are rare.

Testosterone supplements can increase muscle mass and strength in older men with low levels, but long-term effects and risks need more research.

Puerariae Flos extract may help treat hair loss by blocking a hair loss-related enzyme and promoting hair growth.

Testosterone and dihydrotestosterone play a role in women's health issues like excess hair and baldness, and treatments blocking these hormones may help.

Topical estrogen helps hair growth in menopausal women with no major side effects.

Testosterone helps human pancreatic cells increase insulin release.

Balding and low testosterone increase risk of urinary stones.

Honokiol might help reduce male skin aging by maintaining testosterone levels.