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Diagnosing PCOS in teenagers is hard because its symptoms often look like normal puberty, and there's a need for better diagnosis methods and agreement on criteria.

Ovarian SAHA syndrome makes women with PCOS more resistant to insulin and increases their risk of blood sugar problems.

Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.

All treatments reduce hair growth; low dose flutamide most effective with fewer side effects.

Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.

Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.

Isotretinoin improves severe acne without changing androgen or insulin levels but may increase body weight and triglycerides.

In Japan, sex reassignment surgery for gender identity disorder faces challenges and needs better medical support and education.

Effective hirsutism management requires identifying the cause, combining new and traditional treatments, and setting realistic expectations for patients.

Increased HSD11B1 enzyme expression is linked to higher body fat and insulin resistance.

Lower doses of dexamethasone can safely reduce high DHEAS levels in women with androgenic disorders.

AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.

CAH is a genetic disorder affecting cortisol production and causing hormonal imbalances, with treatment and diagnosis varying by form and symptoms.

The conclusion is that managing cholesterol is important for women, especially during pregnancy, breastfeeding, and with PCOS, and involves regular screening and careful treatment choices.

Don't combine abiraterone and spironolactone for prostate cancer treatment as it may worsen the disease.

Male pattern baldness may be caused by factors like poor blood circulation, scalp tension, stress, and hormonal imbalances, but the exact causes are still unclear.

Early diagnosis and treatment of PCOS in teenagers can help prevent more severe adult PCOS.

The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.

Manage women's cholesterol with diet, exercise, and careful treatment choices, especially during pregnancy, PCOS, and menopause.

Benzodiazepines changed hormone levels but did not affect hair growth in women with idiopathic hirsutism.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

Early treatment of PCOS in teens is crucial to prevent long-term health issues like diabetes and heart disease.

A 70-year-old woman with a malignant adrenal tumor improved after surgery and radiotherapy.

The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.

Alopecia X in dogs is a cosmetic issue, not a hormonal disorder, and harmful treatments should be avoided.

Understanding how androgens and their receptors work can lead to improved treatments for skin diseases.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Certain ESR1 gene variations may affect hormone levels and fat distribution in women with high male hormone levels.