research Prevention of Frey Syndrome with Superficial Temporal Fascia Interpositioning: A Retrospective Study
Using superficial temporal fascia helps prevent Frey syndrome after parotid surgery.
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research Cancer Chemotherapy: An Introduction
The book concludes that despite progress, cancer drug treatments have not met the expectations set in the 1960s and 1970s.
research Benefits of Testosterone Replacement and Methods of Substitution
Testosterone replacement therapy helps manage deficiency and has various methods, but requires careful monitoring to avoid side effects.
research Visualizing Androgen Receptor Activity in Male and Female Mice
Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.
research Fibroblast Growth Factor-9 Enhances M2 Macrophage Differentiation and Attenuates Adverse Cardiac Remodeling in the Infarcted Diabetic Heart
Fibroblast Growth Factor-9 (FGF-9) can help improve heart function in diabetic mice after a heart attack by reducing inflammation and harmful changes to the heart's structure.
research Southern African HIV Clinicians Society Gender-Affirming Healthcare Guideline for South Africa
The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.
research Oral Presentations: Abstracts of the Urological Society of Australia and New Zealand Annual Scientific Meeting, Melbourne, Australia
Urologists should monitor mental health in patients taking finasteride due to potential links to suicidal thoughts, adjusting dosage or stopping use if necessary. More research is needed to confirm if finasteride causes these thoughts.
research Abstracts From The 55th European Society Of Human Genetics Conference: E-Posters
Rare ULBP3 gene changes may raise the risk of Alopecia areata, a certain FAS gene deletion could cause a dysfunctional protein in an immune disorder, and having one copy of a specific genetic deletion is okay, but two copies cause sickle cell disease.
research Transgenerational Transmission of Reproductive and Metabolic Dysfunction in Male Progeny of Polycystic Ovary Syndrome
Sons of mothers with polycystic ovary syndrome (PCOS) have a higher risk of obesity and insulin resistance, possibly due to certain genes and factors passed down from their mothers.
research The Need and Management of Hormone Imbalances in Women
The document highlights the prevalence and management of hormonal imbalances in women, which occur during various life stages such as puberty, menstruation, pregnancy, menopause, and post-menopause. Symptoms include irregular periods, hair loss, and mental health issues. It emphasizes the importance of maintaining balanced hormone levels for overall well-being, suggesting natural remedies like exercise and stress reduction. Hormone therapy (HT) is recommended for those unable to achieve balance naturally, as it can alleviate symptoms like hot flashes and reduce risks of chronic conditions. The document includes case reports on hormone imbalances, such as precocious and delayed puberty, PCOS, and menopausal symptoms, demonstrating the need for tailored hormone treatments. It also discusses lifestyle changes to naturally balance hormones and the role of primary care physicians in managing these imbalances.
research Critical Factors in Sample Collection and Preparation for Clinical Metabolomics of Underexplored Biological Specimens
Standardized procedures are crucial for collecting and preparing biological samples to ensure accurate clinical metabolomics results.
research Interpretation Of The Yak Skin Single-Cell Transcriptome Landscape
The study mapped yak skin cells to understand hair growth better.
research Endocrinological Assessment in Transgender Individuals
The document concludes that personalized hormonal treatments are important for transgender individuals and more research is needed for non-binary treatments.
research Relationship of a Novel c.429delC Deletion in Hairless Gene HR with Alopecia in Two Families from Southern Punjab, Pakistan
A new mutation in the Hairless gene causes hair loss in two Pakistani families.
research Female Hyperandrogenism
The document concludes that managing female hyperandrogenism requires a combination of identifying the cause, lifestyle changes, medication, and cosmetic treatments.
research DHEA: Why, When, and How Much? Based on the Conference by Bruno Allolio (Wuerzburg), 50th International Clinical Endocrinology Days Henri-Pierre Klotz, September 2007
DHEA supplementation may improve quality of life, neuropsychological functions, and sexual satisfaction in individuals with adrenal insufficiency, but more research is needed to confirm its safety and effectiveness.
research Male Androgenetic Alopecia
Hair loss in men can be slowed or reversed with treatments like minoxidil and finasteride, but it resumes if treatment stops. It may also indicate early heart disease and obesity.
research Morphological Characteristics and Notes of the Skin in Preclinical Toxicity Assessment
Skin structure complexity and variability are crucial for assessing skin toxicity in safety tests.
research More About X-Linked Testicular Feminization of the Mouse as a Noninducible (is) Mutation of a Regulatory Locus: 5α-Androstan-3α-17β-Diol as the True Inducer of Kidney Alcohol Dehydrogenase and β-Glucuronidase
A specific metabolite, not a receptor protein, triggers the production of certain kidney enzymes, but this process is disrupted in mice with a mutation causing testicular feminization.
research Genetic Regulation of the Androgen Receptor: A Study of Testicular Feminization in the Mouse
The study concludes that a genetic mutation in TFM mice leads to reduced androgen receptor activity, affecting the body's response to male hormones.
research In Vivo and In Silico Evaluation of the Ameliorative Effect of Hesperidin on Finasteride-Induced Testicular Oxidative Stress in Wistar Rats
Hesperidin protects rat testicles from finasteride damage and improves sperm health.
research Anabolic Effect of Dihydrotestosterone in Testicular Feminization Syndrome
Dihydrotestosterone has a reduced effect on muscle-building in people with testicular feminization syndrome, especially after their gonads are removed.
research An Overview of Chemotherapy Side Effects on Patients with Prostate Cancer, Bladder Cancer, and Testicular Cancer at Haji Adam Malik General Hospital Medan from 2020-2022
Chemotherapy for prostate, bladder, and testicular cancer patients commonly causes hair loss, fatigue, and decreased appetite.
research Paternal Finasteride Treatment Can Influence the Testicular Transcriptome Profile of Male Offspring—Preliminary Study
Father's finasteride use may affect son's fertility and testicular function.
research Curcumin Derivatives Inhibit Testicular 17β-Hydroxysteroid Dehydrogenase 3
Curcumin and its derivatives can block an enzyme important for making testosterone, with one derivative being particularly strong.
research Role of 5α-Dihydrotestosterone in Testicular Development of Gilthead Seabream Following Finasteride Administration
DHT affects testicular development and regulates spermatogenesis in some fish.
research Protective Role of Hesperidin in Finasteride-Induced Testicular Toxicity in Adult Male Wistar Rats: Insights Into Oxidative Stress, Apoptosis, and Ultrastructure of Seminiferous Tubules
Hesperidin helps protect against testicular damage caused by finasteride.
research Finasteride Affects the Testicular Physiology of Gilthead Seabream Males
research Effects of Flutamide and Finasteride on Rat Testicular Descent
Androgens, like testosterone, are crucial for early testicular descent in rats.