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Steroidogenesis inhibitors change but don't stop androgen production in prostate cancer.

Testosterone and dihydrotestosterone treatments can help with penile growth in males with 5α-reductase type 2 deficiency, with dihydrotestosterone being more effective in infancy.

Giving melatonin to sheep before the non-breeding season can improve their chances of reproducing in northwest Mexico.

A man's rare adrenal tumor caused feminization and white hair, was removed surgically, and improved after treatment.

Certain maturity signs appear before and after the first release of sperm in boys.

E211 G>A gene linked to lower risk of severe prostate cancer and hair loss.

Using two drugs together, Flutamide and 4-MA, is more effective for blocking male hormones than using each one alone.

Balding and low testosterone increase risk of urinary stones.

A man's baldness improved possibly due to a medication that blocks male hormones.

An 8-year-old boy's early puberty was caused by a rare hormone-secreting brain tumor, which was successfully treated with surgery.

Medical treatments like chemotherapy and radiotherapy can harm sperm production, so freezing sperm before treatment is important for men who want children later.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.

New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.

Early treatment of acne is important to prevent scarring and improve appearance, using medications that can have side effects.

Need better hair loss treatments beyond minoxidil, finasteride, and transplants.

The document does not determine if adults with aphallia are fertile.

The patient's high testosterone was reduced by a medication that suppresses gonadotropin.

Men with Type 2 Diabetes have lower DHT levels, which may affect fertility and lipid profiles.

A certain gene variation is linked to a higher risk of polycystic ovarian syndrome in South Indian women.

The document concludes that current hair loss treatments have limitations and suggests researching new treatments targeting different factors of hair loss.

Finasteride may effectively treat hair loss in Klinefelter Syndrome patients.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.

DrugNet effectively identifies new uses for existing drugs and may save resources in drug development.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

Surgeons must understand the full care process for gender confirmation surgery to help transgender individuals effectively.

The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.

Lowering testosterone speeds up wound healing in male mice.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.