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Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

Scalp cooling can help prevent chemotherapy-induced hair loss with a 50-90% success rate and is safe for patients.

The study found that a specific area of the hair follicle helps start hair growth by reducing the blocking effects on certain cells and controlling growth signals.

The document concludes that there is no agreed-upon best method for measuring drug delivery within hair follicles and more research is needed to validate current techniques.

The arrector pili muscle might play a role in hair loss and needs more research to understand its impact.

The Ovol2-Zeb1 circuit is crucial for skin healing and hair growth by guiding cell movement and growth.

Polyamines are important for hair growth, but more research is needed to understand their functions and treatment potential.

The document concludes that careful design of genetic fate mapping experiments is crucial for accurate cell lineage tracing in mice.

Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.

Gene therapy, especially using atoh1, shows promise for creating functional sensory hair cells in the inner ear, but dosing and side effects need to be managed for clinical application.

TAF4 is important for skin cell growth and helps prevent skin cancer in mice.

Chemotherapy can cause rapid, extensive hair loss, with patterns varying between individuals.

Further research is needed to improve hair regeneration using stem cells and nanomaterials.

The document concludes that primary scarring alopecias cause permanent hair loss, have unpredictable outcomes, and lack definitive treatments, requiring personalized care.

Dying cells can help with faster healing and new hair growth by releasing a growth-promoting molecule.

Home-use cosmetic laser and light devices show modest results for hair removal and acne treatment, but more research is needed for confirmation.

Light microscopy is useful for diagnosing different hair disorders.

Epidermal stem cells have various roles in skin beyond just maintenance, including forming specialized structures and aiding in skin repair and regeneration.

KLF4 is important for maintaining skin stem cells and helps heal wounds.

PRP shows promise for improving facial wrinkles, skin elasticity, and hair growth, but more research is needed to standardize its use and understand its effects.

Understanding how epigenetic regulation affects stem cells is key to cancer insights and new treatments.

Mice can regenerate ear tissue without the p53 protein.

Non-immune factors play a significant role in alopecia areata.

Using systemic drugs as creams for skin conditions shows promise, but more research is needed to confirm their effectiveness and safety.

Anti-cancer treatments can cause reversible hair loss, skin sensitivity, pigmentation changes, nail damage, and skin reactions, with a need for more research on managing these side effects.

Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.

In vivo lineage labelling is better than in vitro methods for identifying and understanding stem cells.

Keratoacanthoma comes from hair follicle cells.

Scientists have made progress in understanding hair follicle stem cells, identifying specific genes and markers, and suggesting their use in treating hair and skin conditions.

Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.