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Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.

Removing the ATR gene in adult mice causes rapid aging and stem cell loss.

Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.

The paper concludes that understanding melanocyte development can help in insights into skin diseases and melanoma diversity.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Most patients with frontal fibrosing alopecia are postmenopausal women, and treatments like finasteride and dutasteride can improve or stabilize the condition.

The conclusion is that certain cell interactions and signals are crucial for hair growth and regeneration.

Alopecia areata is an autoimmune condition causing hair loss, influenced by genetics, stress, and diet, and may be prevented by a high soy oil diet.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.

Tofacitinib is safe and effective for severe alopecia areata, but hair loss may return 2 months after stopping treatment.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.

The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.

Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Cancer cells often have more copies of TERT and TERC genes, which helps them grow and could affect patient outcomes.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

EGFR inhibitors often cause skin problems and other side effects, but these are usually reversible and can be managed to keep patients comfortable.

PRP treatment improves hair growth, and the device used can affect results, with some being more effective.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.