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Reductive stress messes up collagen balance and alters cell signaling in human skin cells, which could help treat certain skin diseases.

Smart biomaterials that guide tissue repair are key for future medical treatments.

Future research should focus on making bioengineered skin that completely restores all skin functions.

The skin produces and processes hormones, affecting both local and overall body functions.

miR-218-5p helps skin and hair growth by targeting SFRP2 and activating a specific signaling pathway.

A machine learning model called CATNIP can predict new uses for existing drugs, like using antidepressants for Parkinson's disease and a thyroid cancer drug for diabetes.

Temporary ROS production in cultured human hair follicles promotes growth and stem cell activation.

Activin activation in skin cells speeds up wound healing without affecting scar quality.

NIPP1 is important for healthy skin and could help treat skin inflammation.

The document concludes that PK/PD modeling is important for determining the safe and effective dosages of drugs.

Exosomes are important for skin health and could help diagnose and treat skin diseases.

Stem cells and their exosomes show promise for repairing tissues and healing wounds when delivered effectively, but more research is needed on their tracking and optimal use.

Wnt/β-catenin and TGF-β pathways affect hair loss, and activating Wnt/β-catenin could be a potential treatment.

Dermal EZH2 controls skin cell growth and differentiation in mice.

Dihydrotestosterone (DHT) is crucial for conditions like male-pattern baldness and acne, and measuring a byproduct, androstanediol glucuronide, is a better way to assess DHT's effects than DHT blood levels.

Type 3 Innate Lymphoid Cells help maintain skin health and balance, and are involved in skin diseases and healing.

Keratin 79 marks a new group of cells that are key for creating and repairing the hair follicle's structure.

New indole-based compounds, particularly cemtirestat, show promise as dual-function drugs for diabetic complications.

Key genes and RNA networks regulate hair growth and follicle density in Rex rabbits.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Wound healing insights can improve regenerative medicine.

A gene mutation in Lama3 is linked to a common type of hair loss.

African plants can treat hair issues and may help with diabetes.

Hair regeneration needs dynamic cell behavior and mesenchyme presence for stem cell activation.

The paper concludes that understanding melanocyte development can help in insights into skin diseases and melanoma diversity.

Muscles can make their own androgens, which may help muscle growth.

Runx genes are important for stem cell regulation and their roles in aging and disease need more research.

The symposium concluded that understanding how different species repair tissue and how this changes with age can help advance regenerative medicine.

Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.

Adding a second method to PROTACs could improve cancer treatment.