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Hair follicle bulge cells are important for hair survival and help heal the skin after injury, which might be relevant for understanding hidradenitis suppurativa.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

The hedgehog signalling pathway is key in skin development and basal cell carcinoma, offering insights for prevention and treatment.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

Hair thinning causes stem cell loss through a process involving Piezo1, calcium, and TNF-α.

Activating Nrf2 in skin cells speeds up wound healing by increasing the growth of certain stem cells.

Changes in testosterone and estrogen receptor genes can affect how men age, influencing body fat, hair patterns, and possibly leading to skin disorders.

Lack of cystatin M/E causes thin hair and dry skin.

The paper suggests that hair loss might be caused by skull growth, not just DHT's effect on hair follicles, and calls for more research.

Premature graying and hair changes can be treated with certain peptides and possibly targeting the endocannabinoid system.

The study suggests that hypothyroidism may cause alopecia areata.

Long-Acting Platelet Rich Plasma therapy can effectively reduce hair shedding, thicken hair, and promote new growth in women with pattern hair loss.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

New treatments for male hair loss show promise but need more research for safety and effectiveness.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

New compounds were made that effectively block a specific enzyme related to androgen conditions.

PTHrP is important for bone formation and may be targeted for osteoporosis treatment and longevity therapies.

Blocking both main energy pathways can stop hair follicle stem cell-induced skin cancer growth.

The research found that a specific skin cell type not only triggers hair growth but also controls hair color, and that aging can lead to hair loss and color changes.

Wnt ligands are crucial for hair growth and repair.

A mutation in the hairless gene speeds up severe itchy skin in mice on a special diet.

Type 2 inflammation helps wound healing by switching immune cells to repair mode.

EGFR inhibitors cause skin issues and hair loss by weakening skin defenses, suggesting antibiotics and targeted treatments can help.

Researchers found potential new targets for treating melanoma and nonmelanoma skin cancers, and identified a possible cause and treatment for male pattern baldness and eczema.

FGF5 gene mutations cause unusually long eyelashes by affecting hair growth regulation.

The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.

Notch signaling disruptions can cause various skin diseases.

A specific gene variant (rs4833095) is linked to a higher risk of alopecia areata in Koreans.