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Early sexual development in children, especially girls, can be treated with hormone therapy to improve adult height and requires support for the child and family.

Cyproterone acetate is a safe treatment that causes mild feminizing effects and is more effective with added estrogens.

Daughters of women with PCOS generally experience normal puberty but may have more body hair and different body fat distribution.

Babies who gain weight quickly, especially in the first 3 months, may start puberty earlier.

Higher fluoride levels may delay puberty in boys.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

High levels of male hormones in pregnant mice cause heart enlargement and poor heart function in their female babies.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

Gonadal dysgenesis, like Turner's and Klinefelter's syndromes, negatively affects bone health, but hormone treatments can help.

Children under 10 can experience hair thinning without hormone issues, and it may improve with treatment.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

The research found that Atypical Progeroid Syndrome has unique symptoms and is not caused by the buildup of a certain mutant protein.

Women with type 1 diabetes often have polycystic ovary syndrome and excess male hormones, which are frequently undiagnosed.

PCOS in teens is hard to diagnose, linked to genetics and lifestyle, and managed with weight loss and medication.

Healthcare providers need better education and policies to serve transgender individuals effectively.

AGA in children needs careful diagnosis due to low androgen levels and possible other causes.

Polycystic Ovary Syndrome (PCOS) is a hormonal disorder in women that can cause infertility and other health issues, and it may be improved by treatments that increase insulin sensitivity.

Hormones, especially androgens, play a key role in causing acne, and treatments like hormone control pills and hormone-blocking medications can help.

The research found that measuring androgens in urine can give extra information about body metabolism and is linked to androgen levels in the blood, especially in young girls.

Hormonal imbalances are a key cause of missed menstrual periods in women.

Swimming in Lake Malawi can lead to schistosomiasis, hepatitis B vaccine might cause temporary hair loss, and certain drinks affect kidney stone risk.

Low selenium intake may delay puberty in boys but not in girls.

Higher early lead exposure is linked to delayed puberty in girls.

Rural Bangladeshi girls mature later than peers in other low and middle-income countries due to poor nutrition and socioeconomic conditions.

Testosterone therapy helps boys with hormone deficiencies develop normal male characteristics and grow properly.

Higher androgen levels during puberty are linked to shorter adult height in boys with Silver-Russell syndrome.

A young Saudi girl with uncontrolled type 1 diabetes and hypothyroidism had two rare conditions, Mauriac syndrome and Van Wyk–Grumbach syndrome.

Gender-affirming therapy can cause skin issues like acne and hair loss in transgender adolescents, and more research is needed on its dermatological effects.