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Hormone replacement therapy may lower the risk of severe COVID-19 outcomes in non-immunosuppressed people and male organ transplant recipients.

High levels of male hormones in pregnant mice cause heart enlargement and poor heart function in their female babies.

Barley extract, specifically procyanidin B-3, can promote hair growth and counteract growth inhibition.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

Children with classic congenital adrenal hyperplasia have thicker heart fat and are at higher risk for heart problems and early atherosclerosis.

Facial plastic surgery has evolved to focus on less invasive techniques and innovative technologies for cosmetic and reconstructive procedures.

Taking 5α-reductase inhibitors with prednisolone can worsen its negative effects on metabolism.

Certain maturity signs appear before and after the first release of sperm in boys.

A 24-month-old Nigerian girl developed early puberty with no family history, needing treatment her family couldn't afford.

Severe acne in a young girl may indicate underlying hormonal issues.

Babies who gain weight quickly, especially in the first 3 months, may start puberty earlier.

A man with both Klinefelter syndrome and primary hyperparathyroidism showed a rare combination of symptoms and genetic patterns.

Reduced AR gene methylation may cause early pubic hair growth in girls.

An 8-year-old boy's early puberty was caused by a rare hormone-secreting brain tumor, which was successfully treated with surgery.

A 20-year-old woman with a rare form of Turner syndrome showed improvement with hormonal therapy and needs comprehensive care.

The document concludes that common menstrual disorders affect adolescent women, with the normal menstrual cycle lasting 21 to 35 days.

Daughters of women with PCOS generally experience normal puberty but may have more body hair and different body fat distribution.

Low selenium intake may delay puberty in boys but not in girls.

A 13-year-old girl's masculine symptoms improved after surgery for a rare adrenal tumor that produced male hormones.

A 13-year-old with 46 XY DSD had ambiguous genitalia due to incomplete masculinization.

Acne and increased body hair in teenage girls are normal but severe cases may need hormone evaluation and treatment can prevent diabetes linked to PCO.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

More research is needed to understand the long-term benefits of insulin-sensitizing drugs for treating adolescents with PCOS.

The research found that measuring androgens in urine can give extra information about body metabolism and is linked to androgen levels in the blood, especially in young girls.

Higher early lead exposure is linked to delayed puberty in girls.

Early diagnosis and treatment of nail lichen planus in children can prevent permanent nail damage.

Satoyoshi syndrome can occur without causing premature ovarian failure.

A 31-year-old woman was diagnosed with Complete Androgen Insensitivity Syndrome much later than usual, leading to a call for earlier detection and treatment guidelines.

A teenage girl with high androgen levels and PCOS developed a rare liver tumor, suggesting a possible link between high androgens and the tumor's growth.

A boy with a new NR5A1 gene mutation has a sex development disorder without affecting his adrenal glands.