Late Diagnosis of Complete Androgen Insensitivity

    April 2019 in “ Journal of the Endocrine Society ”
    Karen Tsai, Tong Liang, Braden Barnett, Jonathan S. LoPresti
    TLDR A 31-year-old woman was diagnosed with Complete Androgen Insensitivity Syndrome much later than usual, leading to a call for earlier detection and treatment guidelines.
    The article discussed a case of a 31-year-old female diagnosed with Complete Androgen Insensitivity Syndrome (CAIS), a rare condition typically identified at menarche. The patient presented with primary amenorrhea, minimal breast development, sparse body hair, and a shallow vaginal canal. Physical examination and lab results confirmed CAIS, showing elevated testosterone, LH, and FSH levels, and a 46, XY karyotype. The patient underwent bilateral orchiectomy and started estrogen replacement therapy. The case highlighted the importance of early diagnosis for effective management and psychosocial support, noting the psychological distress caused by the late diagnosis. The authors emphasized the need for further research to develop evidence-based guidelines for CAIS treatment.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 855 results

      community Fun thought experiment about halting hair loss permamently

      in Research/Science  58 upvotes 6 months ago
      A user proposed genetically engineering scalp stem cells to stop androgen receptors from causing hair loss. Others discussed the feasibility, existing research, and potential issues with this approach, including targeting the correct cells and unintended effects.

      community How does dutasteride regrowth work?

      in Finasteride/Dutasteride  6 upvotes 6 months ago
      A 25-year-old man with hair loss from bleach damage is using oral minoxidil and considering adding Dutasteride for better regrowth and prevention. He seeks advice on Dutasteride's effectiveness and potential benefits over finasteride, and is also curious about RU58841.

      community Can anyone confidently say their erections are the same on fin ?

      in Chat  240 upvotes 5 months ago
      The conversation discusses the impact of finasteride on sexual function, with many users reporting reduced libido and weaker erections despite continuing the treatment to prevent hair loss. Some users suggest checking hormone levels or switching to different dosages or treatments like dutasteride, while others share mixed experiences regarding the severity of side effects.

    Similar Research

    5 / 1000+ results