2 citations
,
January 2020 in “Skin appendage disorders” This article discusses traction alopecia in children and adolescents, emphasizing its occurrence due to hairstyles that exert chronic tension on hair, but reports no new findings.
68 citations
,
August 2009 in “American Journal of Medical Genetics Part A” This study systematically reviewed clinical findings in trichothiodystrophy patients and suggested a new clinico-genetic classification to help better understand the ichthyotic phenotype and its management.
35 citations
,
September 2011 in “The Journal of Dermatology” This article discusses the trichoscopic diagnosis of temporal triangular alopecia, but reports no new clinical results.
3 citations
,
November 1998 in “Pediatrics in review” This article reviews various dermatophyte infections, particularly tinea capitis, and discusses their clinical presentations, diagnosis, and treatment, but reports no new clinical findings.
May 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” This study found that tofacitinib may inhibit CD8+ T cell infiltration in alopecia areata by affecting the linoleic acid metabolism-Mg2+ pathway in a sodium sulfide-induced mouse model, highlighting new insights for clinical diagnosis and treatment strategies.
1 citations
,
January 2024 in “Pharmaceuticals” The researchers reported that dPGS-PCL as a carrier improved the penetration of tofacitinib in an ex-vivo human skin model compared to free tofacitinib, but did not show significant differences in inhibiting IL-6 and IL-8 during short incubation.
17 citations
,
January 2019 in “Dermatologic Therapy” The article in Dermatologic Therapy discusses clinical experiences with using tofacitinib to treat alopecia areata in 63 patients, but no specific results are reported in the abstract.
March 2026 in “Journal of Pakistan Association of Dermatologists” In this quasi-experimental study, 24-week tofacitinib treatment significantly improved hair regrowth in South Asian patients with alopecia areata, but a high relapse rate post-withdrawal signals the need for continuous treatment strategies.
59 citations
,
January 2002 in “Dermatology” This study suggests the existence of a new subtype of alopecia, called 'acute diffuse and total alopecia of the female scalp (ADTAFS)', characterized by acute, diffuse hair loss primarily in women and a rapid recovery.
1 citations
,
February 2022 in “Clinical, Cosmetic and Investigational Dermatology” In this study, researchers found that the thyroxine receptor agonist TDM10842 accelerated the onset of anagen, a hair growth phase, in C3H mice, potentially through activation of the Wnt/beta-catenin and Hedgehog pathways, with Pclaf playing a key role in this process.
2 citations
,
February 2018 in “Journal of dermatology & cosmetology” This article discusses triangular temporal alopecia, highlighting dermoscopy's role in diagnosis and the limited therapeutic options, without reporting new clinical results.
September 1973 in “Primates”
2 citations
,
April 2019 in “Dermatologic Therapy” A patient with alopecia had hair regrowth with tofacitinib but developed a skin reaction, choosing to continue the treatment despite the side effect.
24 citations
,
October 2018 in “JAAD Case Reports” This paper reviews the challenges of treating alopecia areata affecting eyelashes and discusses the risks associated with traditional therapies; it reports no new clinical results.
January 2024 in “Dermatologic therapy” In this study, pediatric patients with alopecia areata treated with systemic tofacitinib showed significant improvement at 12 months, but the small sample size and retrospective design limit conclusions about its effectiveness.
May 2025 in “Frontiers in Pharmacology” This study investigated alopecia areata in a mouse model, finding that tofacitinib may inhibit disease progression by modulating linoleic acid metabolism and magnesium pathways, particularly affecting CD8+ T cell infiltration in hair follicles, offering insights for potential treatments.
November 2025 in “Mendeley Data” In this study, tofacitinib and baricitinib showed comparable efficacy and tolerability under unorthodox weight-stratified dosing in pediatric patients with moderate-to-severe alopecia areata over 24 weeks; however, the unorthodox baricitinib regimen yielded a lower effectiveness in severe cases, emphasizing the importance of adherence to guideline-recommended dosing.
4 citations
,
November 1998 in “Pediatrics in review” This article reviews the characteristics and treatment options for various dermatophyte infections, highlighting that systemic treatment is essential for tinea capitis while topical treatments are generally effective for other types.
June 2025 in “International Journal of Science and Research (IJSR)” This study found that oral tofacitinib at a 5mg twice daily dosage was effective in treating recalcitrant alopecia areata, showing significant improvement in hair regrowth and a 27% reduction in SALT scores over six months, with minimal side effects among the 19 patients monitored.
2 citations
,
September 2024 in “PLoS ONE” This study suggests that combining bendamustine with tucidinostat may improve survival in patients with relapsed or refractory adult T-cell leukemia/lymphoma, highlighting its potential for clinical investigation.
April 2017 in “Leukemia research” This study reported that tofacitinib may be a promising treatment for alopecia areata in adolescents, showing significant hair regrowth with mild adverse effects in a retrospective review.
11 citations
,
November 2019 in “Journal of the American Academy of Dermatology” This study suggests that oral tofacitinib may be an effective treatment for beard regrowth in men with alopecia areata of the beard, with a strong correlation observed between beard and scalp hair regrowth.
4 citations
,
November 2020 in “Acta Dermato Venereologica” In this study, patients with specific skin and scalp conditions, including eczematous lesions, showed significant improvement after two weeks of oral tofacitinib treatment, as evidenced by changes in the trunk lesions.
July 2021 in “British Journal of Dermatology” This report describes a boy with ectodermal dysplasias who was genetically diagnosed due to newly discovered TSPEAR gene variants, which have now been associated with this condition.
October 1984 in “Immunology Today”
3 citations
,
January 2023 in “Science advances” This study found that ablation of Tet2/Tet3 genes in skin epithelial cells altered hair shape and length, leading to hair loss, by affecting chromatin accessibility and gene expression related to hair follicle regulation.
116 citations
,
August 2010 in “Nature” Scientists turned rat thymus cells into stem cells that can help repair skin and hair.
1 citations
,
January 2024 in “Arab Board Medical Journal” This study found that tofacitinib was an effective and well-tolerated treatment for alopecia areata, with significant to moderate hair regrowth in 78% of patients observed.
July 2018 in “Journal of The American Academy of Dermatology” This article discusses current visualization methods for assessing hair restoration therapy responses, noting imprecision in triangulated measurements and patient dissatisfaction with visible tattoos.
December 2019 in “Journal of pediatrics & neonatology” This case report discusses the diagnosis and management of temporal triangular alopecia in a pediatric patient experiencing asymptomatic hair loss, emphasizing its nonprogressive nature and poor prognosis for regrowth.