research Minoxidil Use in Dermatology, Side Effects, and Recent Patents
Minoxidil treats hair loss, promotes growth, has side effects, and has recent patents.
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research WNT Signaling in Disease
The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.
research Physiological Functions of PP2A: Lessons from Genetically Modified Mice
Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.
research Applications of Mesenchymal Stem Cells in Skin Regeneration and Rejuvenation
Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.
research Critical Analysis on Characterization, Systemic Effect, and Therapeutic Potential of Beta-Sitosterol: A Plant-Derived Orphan Phytosterol
Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.
research Systematic Review of Platelet-Rich Plasma Use in Androgenetic Alopecia Compared with Minoxidil, Finasteride, and Adult Stem Cell-Based Therapy
PRP injections may be a safe, effective alternative for hair loss treatment compared to minoxidil and finasteride.
research EdnrB Governs Regenerative Response of Melanocyte Stem Cells by Crosstalk with Wnt Signaling
EdnrB signaling helps melanocyte stem cells regenerate and could be targeted to treat pigmentation issues.
research Sex Hormone-Binding Globulin as an Early Biomarker and Therapeutic Target in Polycystic Ovary Syndrome
SHBG may be a useful early indicator and treatment target for PCOS.
research Bi-Allelic Mutations in LSS, Encoding Lanosterol Synthase, Cause Autosomal-Recessive Hypotrichosis Simplex
Mutations in the LSS gene cause a rare type of hereditary hair loss.
research Enhanced Cutaneous Wound Healing by Functional Injectable Thermo-Sensitive Chitosan-Based Hydrogel Encapsulated Human Umbilical Cord-Mesenchymal Stem Cells
A new hydrogel with stem cells from human umbilical cords improves skin wound healing and reduces inflammation.
research Mutations in the Keratin 85 (KRT85/hHb5) Gene Underlie Pure Hair and Nail Ectodermal Dysplasia
Mutations in the KRT85 gene cause hair and nail problems.
research Realizing the Therapeutic Potential of Neuroactive Steroid Modulators of the GABAA Receptor
Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.
research Androgen Modulation of Wnt/β-Catenin Signaling in Androgenetic Alopecia
Androgens may block hair growth signals, targeting this could treat hair loss.
research Oxygen, Metabolism, and Regeneration: Lessons from Mice
Mice with enhanced regeneration abilities may help develop new regenerative medicine therapies.
research Cellular Senescence in Tissue Repair: Every Cloud Has a Silver Lining
Cell aging can be both good and bad for tissue repair.
research Middle East Medicinal Plants in the Treatment of Diabetes: A Review
Some Middle Eastern plants may help treat diabetes and could be alternatives to current drugs, but more research is needed.
research Systematically Optimized Coenzyme Q10-Loaded Novel Proniosomal Formulation for Treatment of Photo-Induced Aging in Mice: Characterization, Biocompatibility Studies, Biochemical Estimations, and Anti-Aging Evaluation
The new CoQ10 gel protects mouse skin better against aging from UV light than the old gel.
research Exploring Pericyte and Cardiac Stem Cell Secretome Unveils New Tactics for Drug Discovery
New drugs for heart disease may be developed from molecules secreted by stem cells.
research Retinoid-Mediated Stimulation of Steroid Sulfatase Activity in Myeloid Leukemic Cell Lines Requires RARα and RXR and Involves the Phosphoinositide 3-Kinase and ERK-MAP Kinase Pathways
Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.
research Topical Application of Ketoconazole Stimulates Hair Growth in C3H/HeN Mice
Putting ketoconazole on the skin can help mice grow hair.
research Application of Nanoemulsions in Cosmetics
Nanoemulsions improve stability and delivery of active ingredients in cosmetics for skin and hair care.
research Exogenous and Endogenous Lipids of Human Hair
Removing external lipids from hair reduces moisture and increases strength, while removing internal lipids decreases water permeability.
research The Use of Polyethylenimine–DNA to Topically Deliver hTERT to Promote Hair Growth
Using polyethylenimine-DNA to deliver the hTERT gene can stimulate hair growth and may be useful in treating hair loss, but there could be potential cancer risks.
research Promoting Axonal Regeneration Through Exosomes: An Update of Recent Findings on Exosomal PTEN and mTOR Modifiers
Exosomes help nerve fibers grow by affecting specific cell signaling pathways.
research Compilation of a Comprehensive Gene Panel for Systematic Assessment of Genes That Govern an Individual’s Drug Responses
Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.
research Lipid Losses and Barrier Function Modifications of the Brown-to-White Hair Transition
White hair has less lipid content and absorbs water differently than brown hair.
research Skin Disorders Associated with the COVID-19 Pandemic: A Review
The review found that COVID-19 can cause skin problems, including rashes and issues from wearing PPE, and suggests more research and protective measures for healthcare workers.
research Effect of Finasteride Particle Size Reduction on Its Pharmacokinetic, Tissue Distribution, and Cellular Permeation
Smaller finasteride particles increase effectiveness in treating hair loss.
research Expression Analysis of the Type I Keratin Protein Keratin 33A in Goat Coat Hair
Keratin 33A is a key protein in goat winter coats, especially in high-producing breeds.
research External Lipid Function in Ethnic Hairs
African hair has the most lipids, while Caucasian hair is more hydrated and stronger.