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This study observed that overexpressing TSPO in the hippocampal dentate gyrus of mice led to significant anxiolytic and antidepressant-like effects, potentially mediated by increased allopregnanolone synthesis.

Hair follicles help guide nerve growth, improving touch recovery in skin grafts.

In this study, researchers found that during late pregnancy, neuroactive steroid fluctuations increase the number of extrasynaptic GABAA receptors in rat hippocampal cells.

This review explores the historical development of theories on physiological tissue regeneration, particularly focusing on peripheral nerve regeneration, and emphasizes the need for new experiments and perspectives without providing new empirical findings.

This study presents an improved reference genome for the African spiny mouse, which may aid in understanding its tissue regeneration at the molecular level.

Ectodysplasin-A1 is crucial for developing hair, teeth, and glands.

In this study, researchers found that the expression of laminin, collagen type IV, and fibronectin in fetal human skin begins in hair follicle germs and extends to epidermal cells by 21 weeks gestational age.

This article describes a protocol for using bioengineered techniques to regenerate functional hair follicles and their stem cell niches by manipulating epithelial and mesenchymal cells.

In this study, researchers used single-cell RNA sequencing to define and locate three distinct cell states of melanocytes in mouse skin development, potentially aiding the understanding of abnormal melanocyte differentiation.

This study found that somatosensory axons innervating Merkel cells in adult mouse skin exhibit significant plasticity, influenced by epithelial and neural factors, indicating a complex interaction in maintaining homeostasis.

This paper discusses the multipotency of cyst cells and proposes that understanding molecular circuits in cyst formation could enable engineering of desired stem cell culture phenotypes, but reports no new experimental outcomes.

This study reveals that epidermal stem cell differentiation in mice involves dynamic transcriptional changes, with Keratin-10 transcription preceding gradual chromatin compaction shifts associated with differentiation.

This study found that the proteins GDNF, NTN, GFRα-1, GFRα-2, and c-Ret are differentially expressed during various stages of the human hair follicle cycle, with potential implications for hair biology.

This study found that palmitoylethanolamide may stimulate allopregnanolone synthesis and reduce oxidative stress in astrocytes through PPAR-α activation, suggesting a neuroprotective role.

This study found that mouse embryoid bodies adhered quickly and differentiated efficiently into cardiomyocytes on negatively charged poly(sodium p-styrene sulfonate) hydrogels, similar to their behavior on gelatin-coated polystyrene.

This study found that over-expression of thymosin beta-4 in transgenic mice accelerated wound healing and hair growth, but did not affect tumor progression despite stimulating tumor metastasis.

This study demonstrated that in live rodents, actin filaments adjust their structure to facilitate membrane transfer between cellular compartments with different biophysical properties.

This study reports that corneal transient amplifying cells can be reprogrammed into epidermal cells capable of forming hair follicles in response to embryonic dermis signals.

This study re-examined the structure of lanceolate endings in rat vibrissae, suggesting that their apical cones may function as a transducer site for detecting hair movements.

In this study, rat vibrissa follicles transplanted into mice demonstrated survival, partial sympathetic nerve reinnervation, and increased norepinephrine levels 37 days post-implantation, suggesting potential for hair growth despite not returning to normal nerve function.

This study suggests that new cells are incorporated into the dermal papilla during the early anagen phase of the hair cycle, which may influence hair growth consistency and follicle size changes.

This study describes a protocol for inducing endogenous reactive oxygen species in mouse skin, which stimulates tissue regeneration and promotes burn healing and hair follicle growth.

This study found that multipotent neural crest stem cells from hair follicles require a full set of reprogramming factors for induced pluripotent stem cell induction, similar to fibroblasts.

This document, authored by Jack Schaffer, establishes prior art for methods aimed at treating disorders related to tissue function by restoring bioelectric communication among cells, preceding specific applications for conditions like androgenic alopecia and age-related sexual dysfunction.

This study demonstrated that Gelfoam® histoculture supports extensive growth of both hair shafts and sensory nerves from isolated mouse whisker follicles over prolonged periods.