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This study observed that a self-emulsifying drug delivery system for finasteride significantly enhanced bioavailability in rats compared to commercial tablets, but the formulation was found to be thermodynamically unstable.

This study demonstrates that a 3D-printed agarose microwell platform supports the growth of size-uniform, viable NSCLC cancer spheroids, and can effectively evaluate drug responses using limited tumor material from biopsies, particularly with EGFR tyrosine kinase inhibitors gefitinib and osimertinib.

This study suggests that fatigue, joint pain, and light sensitivity are significant impacts for systemic lupus erythematosus patients, highlighting areas of unmet need in current treatment options.

This study observed an alopecia syphilitica-like pattern of hair loss in a woman with frontal fibrosing alopecia, suggesting it may be another atypical presentation of the condition.

In this case report, researchers identified a potential adverse skin reaction, called SDRIFE or Baboon syndrome, caused by the drug tofacitinib in a 19-year-old woman being treated for alopecia subtotalis, leading the authors to recommend discontinuation of the drug.

This study found that deleting ceramide synthase 4 in skin epidermis stem cells disrupts hair follicle and skin barrier function, leading to immune responses similar to atopic dermatitis, due to imbalances in lipid composition affecting differentiation.

This study found that specific genetic variations in the IRF2BP2 gene influence fleece structure in sheep, with one variant completely determining coat type and another significantly modifying fiber characteristics, providing valuable insights for improving fleece quality through selective breeding.

This study developed a synchronized fluorescence spectroscopic approach to quantify finasteride and tadalafil in various forms, achieving high accuracy with %recoveries of about 99.62% and 100.19% respectively, and demonstrated superior environmental friendliness compared to previous methods.

In this study, a silk-inspired hydrogel system was developed that combines photodynamic therapy and wound healing, which may significantly reduce melanoma recurrence and enhance healing of infected wounds.

In this report, the authors highlight the diagnostic challenge of distinguishing syphilitic alopecia from alopecia areata, noting that the characteristic exclamation mark hairs of alopecia areata can also appear in syphilitic alopecia, underscoring the need for a comprehensive diagnostic approach.

This report describes a case of SAPHO syndrome likely triggered by escalated dosing of infliximab in a 21-year-old woman, highlighting the complex nature of infliximab-induced adverse events, and suggesting a potential autoimmune basis involving two distinct pathophysiologies for SAPHO syndrome.

This study reported that ZSYY001, a nanoparticle formulation of polymeric micellar paclitaxel, showed promising antitumor activity and was safe and well-tolerated in preclinical models and a phase I trial, without acute hypersensitivity reactions at doses up to 390 mg/m².

This study demonstrated that safflower seeds can be engineered to express oleosin-FGF10, which showed a dose-dependent effect on cellular proliferation, potentially facilitating scalable protein production.

This study developed two comprehensive patient-reported outcome measures for systemic lupus erythematosus to assess symptom fluctuations and impacts, following FDA guidelines, which may aid in clinical studies and practice.

This study developed a Neusilin® US2-based solid self-nanoemulsifying drug delivery system for finasteride that showed improved stability and drug delivery, with complete dissolution comparable to standard Propecia® tablets.

This study identified a fungal sulfotransferase enzyme, FgSULT1, from *Fusarium graminearum*, expanding the sulfotransferase superfamily and offering new biocatalytic methods for producing bioactive sulfates.

Sorafenib can cause a temporary skin condition that goes away after stopping the drug.

This study found that mice lacking the Sept4/ARTS gene had more hair follicle stem cells and improved wound healing, suggesting apoptosis regulation as a potential target in regenerative medicine.

This study reported that Sintilimab combined with chemotherapy may improve outcomes in advanced NSCLC patients but carries a higher risk of certain side effects, including hypothyroidism.

This study found that probiotic-functionalized silk fibroin/alginate scaffolds, loaded with Lactobacillus casei, promoted scarless wound healing and hair follicle regeneration in infected wounds in rats.

Finasteride significantly reduced tics and obsessive-compulsive symptoms in Tourette syndrome patients.

In this study, ACF sponges with 10% fucoidan significantly promoted wound healing and hair follicle regeneration in rats, showing improved hemostatic and antibacterial performance compared to other formulations.

This theoretical paper proposes that a subset of Post-Finasteride Syndrome cases may be driven by a gut-derived toxic process involving hydrogen sulphide-producing bacteria, suggesting that the small intestinal microbiome could be a potential target for treating this condition.

This study found that intermittent treatment with FTI lonafarnib and sulforaphane may be a promising therapeutic approach for children with Hutchinson-Gilford progeria syndrome, as it improved the cellular phenotype.

This study identified a novel SCF mRNA splice variant in white merino sheep skin, which may play a role in hair follicle melanogenesis.

Post-finasteride syndrome causes various symptoms in men using finasteride, with no known cure.

Syphilitic alopecia is a rare hair loss condition in secondary syphilis that looks similar to another condition but can be diagnosed with specific tests and responds to antibiotics.

This study found that scurvy is associated with the development of Sjögren's syndrome symptoms, which resolved with ascorbic acid repletion.

In this study, HPH-15, a newly synthesized compound, demonstrated potential in reducing skin fibrosis in a mouse model by targeting underlying pathogenic mechanisms and exhibited a good safety profile, warranting further clinical trials for fibrotic skin disorders like systemic sclerosis.