15 citations
,
November 2015 in “Journal of Cosmetic Dermatology” This study reviews existing literature on botanicals for androgenetic alopecia, noting a growing interest and emphasizing research on hair growth stimulants, especially involving green tea and other specific botanicals.
14 citations
,
April 2021 in “Biology” This study found that ethanol extract of Tubtim Chumphae rice bran downregulates SRD5A gene expression, similarly to finasteride, suggesting potential use as an anti-hair loss product.
14 citations
,
January 2020 in “Mediterranean Journal of Rheumatology” This review discusses the development of Janus kinase inhibitors for dermatologic diseases and reports no new results; the authors note the need for further research on their efficacy and safety.
14 citations
,
February 1994 in “Tetrahedron Letters” This study found that using anhydrous cerium(III) chloride with alkyl Grignard reagents significantly improved the addition to sterically hindered 17-ketosteroids, resulting in high yields and stereoselectivity.
14 citations
,
November 1982 in “British Journal of Dermatology” This article discusses whether testosterone's metabolism to 5α-dihydrotestosterone is necessary for androgenic effects in the skin but reports no new experimental results.
13 citations
,
December 2019 in “Nutrients” In human follicular cells, this study found that an Annurca apple-based dietary supplement may stimulate the production of hair keratins, suggesting potential benefits for hair growth.
13 citations
,
August 1995 in “The Journal of Steroid Biochemistry and Molecular Biology” This study found that the pH dependency of rat steroid 5α-reductase type II isozyme significantly affects its kinetic properties, including Vmax and Km, suggesting past discrepancies in literature may arise from these pH variances during assays.
12 citations
,
February 2007 in “Facial Plastic Surgery” This review discusses advancements in surgical hair restoration techniques, highlighting that modern follicular unit hair transplanting now achieves much more natural and undetectable results than previous methods, but reports no new clinical findings.
12 citations
,
April 1995 in “Journal of Medicinal Chemistry” In this study, 4-substituted N-(1,1-dimethylethyl)-3-oxo-4-androstene-17.beta.-carboxamides were synthesized and evaluated in vitro as potential 5 alpha-reductase inhibitors and antiandrogens.
12 citations
,
December 1985 in “Dicp-The annals of pharmacotherapy” This case study observed hair shedding in an 8 1/2-year-old girl treated with carbamazepine, which ceased after stopping the medication.
11 citations
,
August 2000 in “Journal of Endocrinology” In this study, treatment with DHEA induced mild to moderate hyperplasia of sebaceous glands in ovariectomized rats, which was prevented by the antiandrogen Flutamide but not by the antiestrogen EM-800.
9 citations
,
April 2021 in “Expert opinion on pharmacotherapy” This review highlights that clascoterone, a newly FDA-approved topical androgen antagonist, effectively reduces both non-inflammatory and inflammatory acne lesions with no systemic effects, making it a promising new option for acne treatment in both male and female patients.
9 citations
,
March 2021 in “Hormones” This review discusses how COVID-19 may affect gonadal function and potential gender differences, but reports no clinical results; it highlights possible mechanisms and new treatment approaches from recent literature.
9 citations
,
November 2018 in “International Journal of Medical Reviews” This review discusses the prevalence and etiologies of sexual dysfunction in young men, highlighting the increased recognition of organic causes alongside psychosomatic factors, and reports no new clinical results.
9 citations
,
October 1988 in “Clinics in Dermatology” This paper discusses androgenetic alopecia, its causes, synonyms, and patterns, but reports no new findings or clinical results.
8 citations
,
January 2022 in “Burns and trauma” This review discusses the role of extracellular vesicles from specific skin cells in wound healing, emphasizing their potential in regenerative medicine and reporting no new experimental results.
8 citations
,
July 2020 in “International Journal of Pharmaceutics” In this study, complexation with cyclodextrins was reported to increase the solubility of FIN for potential use in aqueous formulations for treating male androgenic alopecia.
8 citations
,
July 2011 in “Critical reviews in analytical chemistry” This article discusses fluconazole's pharmacological and physicochemical properties and methods for its analysis, but reports no new clinical results.
8 citations
,
January 1996 in “Gynecological Endocrinology” This review evaluates therapies for hyperandrogenism, highlighting cyproterone acetate as the preferred treatment due to its potency and tolerability in managing symptoms in women.
8 citations
,
January 1996 in “Springer eBooks” This article discusses the minimal research on hair growth physiology and highlights Dr. Masumi Inaba's contributions to understanding androgenetic alopecia, but reports no new experimental results.
8 citations
,
May 1982 in “Journal of Endocrinology/Journal of endocrinology” This study suggests that in rat skin, testosterone itself may play a more significant role in androgen action than 5α-dihydrotestosterone, unlike in the prostate where 5α-DHT is more dominant.
7 citations
,
September 2020 in “Journal of Cosmetic Dermatology” This study found that the prevalence of androgenetic alopecia was significantly higher among smokers compared to nonsmokers, though the severity wasn't linked to smoking intensity.
7 citations
,
December 2019 in “American Journal of Clinical Dermatology” This review discusses the potential efficacy of topical antiandrogen therapies for treating androgenetic alopecia and acne vulgaris, finding promising results but highlighting the need for more comprehensive studies.
7 citations
,
July 2019 in “International Journal of Molecular Sciences” This study found that PGA-4HGF nanoparticles enhanced hair growth in mice more effectively than 4HGF alone by increasing anagen phase duration and dermal papilla cell proliferation.
7 citations
,
September 2006 in “Clinical lymphoma & myeloma” This review discusses various treatment challenges and toxicities in patients with relapsed follicular lymphoma and suggests that novel therapies could improve outcomes by reducing exposure to harmful chemotherapy cycles.
7 citations
,
May 1978 in “International Journal of Dermatology” Recent hair loss research shows some progress, especially in understanding male pattern baldness, but effective treatments for many types of hair loss are still lacking.
6 citations
,
November 1997 in “International Journal of Dermatology” This study found that women with acne and oligomenorrhea have higher levels of biologically active testosterone compared to those with acne and normal menstrual cycles.
5 citations
,
December 2022 in “Research in Biotechnology and Environmental Science” This bibliometric review analyzes trends in published research on ocean pollution biodegradation and bioremediation over time, reporting a notable growth in related publications from 2010 to 2022.
5 citations
,
December 2021 in “Physiological Research” This paper reviews the role of androgens in SARS-CoV-2 infection and their potential impact on disease severity, suggesting androgen-targeting strategies might influence outcomes, but reports no new clinical results.
5 citations
,
May 2021 in “Veterinary medicine and science” In this study, cosyntropin-induced cortisol spikes did not affect hair cortisol concentration in captive grizzly bears, contrasting with stress responses observed in free-ranging bears during capture.