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Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

The document concludes that accurate diagnosis of ichthyosis is crucial for treatment and genetic advice, and ongoing research is needed for better therapies.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Skin grafts on mice can cause an immune response leading to hair loss, useful for studying human hair loss conditions.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Hair color production is closely linked to the active growth phase of hair in mice and may also influence hair growth itself.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Mutations in the PADI3 gene are linked to a higher risk of scarring hair loss in women of African descent.

The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.

Minoxidil and finasteride effectively treat hair loss.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

Genetics and hormones play a role in male and female hair loss, but more research is needed to fully understand it.

Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.

New treatments for Alopecia Areata, like JAK inhibitors, show promise for hair regrowth and are likely to change future treatment approaches.

Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.

Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.

The length of the CAG repeat in the androgen receptor gene affects the risk and progression of prostate cancer, BPH, infertility, and undermasculinized genitalia.

Mutations in the hairless gene in mice affect its expression and lead to a range of developmental issues in multiple tissues.

Use "female pattern hair loss" term, assess androgen excess, treat with minoxidil and other medications if needed.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.

Genes play a significant role in male-pattern baldness, and understanding them could lead to new treatments and insights into related health issues.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

People with atopic dermatitis are more likely to develop other skin conditions due to shared genetics and immune pathways.

Genotyping for NUDT15 p.Arg139Cys can help predict thiopurine side effects in Japanese IBD patients.

Current treatments for male pattern baldness include minoxidil and finasteride, with new options being developed.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Mice are useful for researching human hair loss and testing treatments, despite some differences between species.